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cd4 [plasma membrane]
Stable Identifier
R-XTR-167542
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
plasma membrane
Synonyms
CD4, A0A803K8J4
Locations in the PathwayBrowser
Expand all
Immune System (Xenopus tropicalis)
Adaptive Immune System (Xenopus tropicalis)
Regulation of T cell activation by CD28 family (Xenopus tropicalis)
Co-inhibition by PD-1 (Xenopus tropicalis)
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Xenopus tropicalis)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
TCR signaling (Xenopus tropicalis)
Generation of second messenger molecules (Xenopus tropicalis)
Phosphorylation of PLC-gamma1 (Xenopus tropicalis)
ZAP-70 and ITK tyrosine kinases [plasma membrane] (Xenopus tropicalis)
Activated ZAP-70 [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
Phosphorylation of CD3 and TCR zeta chains (Xenopus tropicalis)
Activation of Lck (Xenopus tropicalis)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
Inactivation of Lck by Csk (Xenopus tropicalis)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
Phosphorylation of ITAM motifs in CD3 complexes (Xenopus tropicalis)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
Translocation of ZAP-70 to Immunological synapse (Xenopus tropicalis)
Activation of ZAP-70 (Xenopus tropicalis)
Activated ZAP-70 [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
phospho tyrosine ZAP-70 [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
Phosphorylation of ZAP-70 by Lck (Xenopus tropicalis)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
phospho tyrosine ZAP-70 [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
Recruitment of ZAP-70 to phosphorylated ITAMs (Xenopus tropicalis)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
Signaling by Interleukins (Xenopus tropicalis)
Other interleukin signaling (Xenopus tropicalis)
CD4 binds Interleukin-16 (Xenopus tropicalis)
CD4:IL16(1212-1332) [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
cd4 [plasma membrane] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:A0A803K8J4
Gene Names
cd4
Reference Genes
ENSEMBL:ENSXETG00000036441
KEGG:xtr:100491070 cd4
UCSC:A0A803K8J4 cd4
Reference Transcript
RefSeq:XM_002941684.4 cd4
RefSeq:XM_031906724.1 cd4
Other Identifiers
100491070
GO:0016020
Participates
as a member of
AP-2 dileucine-containing cargo [plasma membrane] (Xenopus tropicalis)
as a component of
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane] (Xenopus tropicalis)
CD4:IL16(1212-1332) [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Xenopus tropicalis)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Xenopus tropicalis)
as an input of
CD4 binds Interleukin-16 (Xenopus tropicalis)
Inferred From
CD4 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
XP_002941730.2
,
XP_031762584.1
ENSEMBL
ENSXETP00000104201
,
ENSXETP00000106176
,
ENSXETP00000116741
,
ENSXETT00000121308
,
ENSXETG00000036441
,
ENSXETT00000116630
,
ENSXETT00000108635
,
ENSXETP00000116703
,
ENSXETT00000114445
Xenbase
XB-GENE-22201034
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