Reactome | gna14 [plasma membrane]

gna14 [plasma membrane]

Stable Identifier

R-XTR-167453

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

plasma membrane

Synonyms

GNA14, Q66JF0

Locations in the PathwayBrowser

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Hemostasis (Xenopus tropicalis)

- Platelet activation, signaling and aggregation (Xenopus tropicalis)
  - Signal amplification (Xenopus tropicalis)
    - ADP signalling through P2Y purinoceptor 1 (Xenopus tropicalis)
      - Dissociation of the P2Y purinoceptor 1:Gq complex (Xenopus tropicalis)
        
        ADP:P2RY1:G-protein Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        G protein-GTP [plasma membrane] (Xenopus tropicalis)
        
        G protein alpha:GTP complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
        
        G protein alpha:GTP complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
      - P2Y purinoceptor 1 activates MAP kinase p38 alpha (Xenopus tropicalis)
        
        G protein alpha:GTP complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
    - Thromboxane signalling through TP receptor (Xenopus tropicalis)
      - Activated TP receptor binds G-proten Gq (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
        
        TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
      - Dissociation of the TP:Gq complex (Xenopus tropicalis)
        
        G protein alpha:GTP complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
        
        TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        G protein-GTP [plasma membrane] (Xenopus tropicalis)
        
        G protein alpha:GTP complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
      - Gq activation by TP receptor (Xenopus tropicalis)
        
        TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        G protein-GTP [plasma membrane] (Xenopus tropicalis)
        
        G protein alpha:GTP complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
        
        TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
  - Thrombin signalling through proteinase activated receptors (PARs) (Xenopus tropicalis)
    - Thrombin-activated PARs activate Gq (Xenopus tropicalis)
      - Thrombin-activated PAR:Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        G protein-GTP [plasma membrane] (Xenopus tropicalis)
        
        G protein alpha:GTP complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
      - Thrombin-activated PARs:Gq (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
    - Thrombin-activated PARs binds G-protein Gq (Xenopus tropicalis)
      - Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
      - Thrombin-activated PARs:Gq (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
    - Thrombin-activated PARs:Gq (active) dissociate (Xenopus tropicalis)
      - G protein alpha:GTP complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)
      - Thrombin-activated PAR:Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        G protein-GTP [plasma membrane] (Xenopus tropicalis)
        
        G protein alpha:GTP complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)
        
        gna14 [plasma membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q66JF0

Gene Names

gna14

Reference Genes

BioGPS Gene:493416 gna14

ENSEMBL:ENSXETG00000003619

KEGG Gene (Xenopus tropicalis):493416 gna14

Monarch:493416 gna14

NCBI Gene:493416 gna14

Reference Transcript

RefSeq:NM_001008053.2 gna14

Other Identifiers

493416

GO:0000166

GO:0001664

GO:0003824

GO:0003924

GO:0005525

GO:0007165

GO:0007186

GO:0016787

GO:0019001

GO:0023052

GO:0031683

Participates

as a member of

G-protein alpha (q/11/14/15) [plasma membrane] (Xenopus tropicalis)

Inferred From

GNA14 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001008054.1

Xenbase

XB-GENE-945095

Ensembl

ENSXETG00000003619, ENSXETT00000007809, ENSXETP00000007809

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