Reactome | ABI [cytosol]

ABI [cytosol]

Stable Identifier

R-XTR-1671649

Type

Set [CandidateSet]

Species

Xenopus tropicalis

Compartment

cytosol

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Innate Immune System (Xenopus tropicalis)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Xenopus tropicalis)
    - Regulation of actin dynamics for phagocytic cup formation (Xenopus tropicalis)
      - (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Xenopus tropicalis)
        
        Mother filament:branching complex [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC [cytosol] (Xenopus tropicalis)
        
        ABI [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC [cytosol] (Xenopus tropicalis)
        
        ABI [cytosol] (Xenopus tropicalis)
      - ABL phosphorylates WAVEs (Xenopus tropicalis)
        
        WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        WAVE Regulatory Complex [cytosol] (Xenopus tropicalis)
        
        ABI [cytosol] (Xenopus tropicalis)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC [cytosol] (Xenopus tropicalis)
        
        ABI [cytosol] (Xenopus tropicalis)
      - Detachment of WASP/WAVE (Xenopus tropicalis)
        
        Mother filament:branching complex [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC [cytosol] (Xenopus tropicalis)
        
        ABI [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC [cytosol] (Xenopus tropicalis)
        
        ABI [cytosol] (Xenopus tropicalis)
      - RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Xenopus tropicalis)
        
        WAVE Regulatory Complex [cytosol] (Xenopus tropicalis)
        
        ABI [cytosol] (Xenopus tropicalis)
        
        WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        WAVE Regulatory Complex [cytosol] (Xenopus tropicalis)
        
        ABI [cytosol] (Xenopus tropicalis)
      - p-ERK phosphorylates WAVEs and ABI (Xenopus tropicalis)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC [cytosol] (Xenopus tropicalis)
        
        ABI [cytosol] (Xenopus tropicalis)

Participants

members

abi1 [cytosol] (Xenopus tropicalis)

candidates

ABI2 [cytosol] (Xenopus tropicalis)

Participant Of

hasComponent

Inferred From

ABI [cytosol] (Homo sapiens)

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