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traf6 [cytosol]
Stable Identifier
R-XTR-166366
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
TRAF6, Q28DL4
Locations in the PathwayBrowser
Expand all
Immune System (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
Alpha-protein kinase 1 signaling pathway (Xenopus tropicalis)
ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:TRAF6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:TRAF6 oligomer [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:TRAF6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:TRAF6 oligomer [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
Toll-like Receptor Cascades (Xenopus tropicalis)
Toll Like Receptor 10 (TLR10) Cascade (Xenopus tropicalis)
MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
TRAF6 binds MEKK1 (Xenopus tropicalis)
MEKK1:activated TRAF6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 2 (TLR2) Cascade (Xenopus tropicalis)
Toll Like Receptor TLR1:TLR2 Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
TRAF6 binds MEKK1 (Xenopus tropicalis)
MEKK1:activated TRAF6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
Toll Like Receptor TLR6:TLR2 Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
TRAF6 binds MEKK1 (Xenopus tropicalis)
MEKK1:activated TRAF6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 4 (TLR4) Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
TRAF6 binds MEKK1 (Xenopus tropicalis)
MEKK1:activated TRAF6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 5 (TLR5) Cascade (Xenopus tropicalis)
MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
TRAF6 binds MEKK1 (Xenopus tropicalis)
MEKK1:activated TRAF6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Xenopus tropicalis)
MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
TRAF6 binds MEKK1 (Xenopus tropicalis)
MEKK1:activated TRAF6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 9 (TLR9) Cascade (Xenopus tropicalis)
MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
TRAF6 binds MEKK1 (Xenopus tropicalis)
MEKK1:activated TRAF6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Deubiquitination (Xenopus tropicalis)
Ovarian tumor domain proteases (Xenopus tropicalis)
OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA (Xenopus tropicalis)
OTUB1,(OTUB2):RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Xenopus tropicalis)
RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Xenopus tropicalis)
OTUD7B,TNFAIP3,ZRANB1:TRAF6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Xenopus tropicalis)
OTUD7B,TNFAIP3,ZRANB1:TRAF6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
Ub-specific processing proteases (Xenopus tropicalis)
USP4 deubiquitinate TRAF2,TRAF6 (Xenopus tropicalis)
TRAF2, TRAF6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Death Receptor Signaling (Xenopus tropicalis)
p75 NTR receptor-mediated signalling (Xenopus tropicalis)
p75NTR signals via NF-kB (Xenopus tropicalis)
p75NTR recruits signalling complexes (Xenopus tropicalis)
IRAK interacts with TRAF6 (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
MYD88 dissociates (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
TRAF6 is auto-ubiquitinated (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
p62 is recruited and forms a complex with TRAF6 (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Xenopus tropicalis)
traf6 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:Q28DL4
Gene Names
traf6
Reference Genes
BioGPS Gene:493524 traf6
ENSEMBL:ENSXETG00000007549
KEGG Gene (Xenopus tropicalis):493524 traf6
Monarch:493524 traf6
NCBI Gene:493524 traf6
Reference Transcript
RefSeq:NM_001008161.2 traf6
Other Identifiers
493524
GO:0003824
GO:0004842
GO:0005164
GO:0005634
GO:0005737
GO:0005811
GO:0005938
GO:0007165
GO:0008270
GO:0012501
GO:0016567
GO:0016740
GO:0023052
GO:0035556
GO:0036211
GO:0042981
GO:0043122
GO:0043226
GO:0046872
GO:0140096
Participates
as a member of
RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Xenopus tropicalis)
TRAF2, TRAF6 [cytosol] (Xenopus tropicalis)
as a component of
OTUD7B,TNFAIP3,ZRANB1:TRAF6 [cytosol] (Xenopus tropicalis)
IL1R1:IL1:IL1RAP:p-T342,T345,S346-IRAK4:MYD88 dimer:TOLLIP:p-2S,S376,T,T209,T378-IRAK1:TRAF6 [plasma membrane] (Xenopus tropicalis)
TRAF6 homotrimer [cytosol] (Xenopus tropicalis)
MEKK1:activated TRAF6 [cytosol] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:TRAF6 [cytosol] (Xenopus tropicalis)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:TRAF6 oligomer [cytosol] (Xenopus tropicalis)
as an input of
TRAF6 binds MEKK1 (Xenopus tropicalis)
IRAK interacts with TRAF6 (Xenopus tropicalis)
TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex (Xenopus tropicalis)
ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 (Xenopus tropicalis)
Other forms of this molecule
traf6 [cytosol]
traf6 [cytosol]
traf6 [endosome membrane]
traf6 [plasma membrane]
traf6 [cytosol]
Inferred From
TRAF6 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001008162.2
Xenbase
XB-GENE-480628
Ensembl
ENSXETP00000111342
,
ENSXETP00000016445
,
ENSXETT00000106730
,
ENSXETT00000016445
,
ENSXETG00000007549
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