Reactome | ASH2L [nucleoplasm]

ASH2L [nucleoplasm]

Stable Identifier

R-XTR-1629834

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

F7B5C3

Locations in the PathwayBrowser

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Gene expression (Transcription) (Xenopus tropicalis)

- RNA Polymerase II Transcription (Xenopus tropicalis)
  - Generic Transcription Pathway (Xenopus tropicalis)
    - Transcriptional regulation by RUNX1 (Xenopus tropicalis)
      - RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Xenopus tropicalis)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Xenopus tropicalis)
        
        Core MLL complex [nucleoplasm] (Xenopus tropicalis)
        
        ASH2L [nucleoplasm] (Xenopus tropicalis)
        
        H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        Core MLL complex [nucleoplasm] (Xenopus tropicalis)
        
        ASH2L [nucleoplasm] (Xenopus tropicalis)
        
        H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        Core MLL complex [nucleoplasm] (Xenopus tropicalis)
        
        ASH2L [nucleoplasm] (Xenopus tropicalis)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Xenopus tropicalis)
        
        Core MLL complex [nucleoplasm] (Xenopus tropicalis)
        
        ASH2L [nucleoplasm] (Xenopus tropicalis)
        
        H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        Core MLL complex [nucleoplasm] (Xenopus tropicalis)
        
        ASH2L [nucleoplasm] (Xenopus tropicalis)
        
        H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        Core MLL complex [nucleoplasm] (Xenopus tropicalis)
        
        ASH2L [nucleoplasm] (Xenopus tropicalis)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Xenopus tropicalis)
        
        H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        Core MLL complex [nucleoplasm] (Xenopus tropicalis)
        
        ASH2L [nucleoplasm] (Xenopus tropicalis)
        
        H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        Core MLL complex [nucleoplasm] (Xenopus tropicalis)
        
        ASH2L [nucleoplasm] (Xenopus tropicalis)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        Core MLL complex [nucleoplasm] (Xenopus tropicalis)
        
        ASH2L [nucleoplasm] (Xenopus tropicalis)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Xenopus tropicalis)
        
        Core MLL complex [nucleoplasm] (Xenopus tropicalis)
        
        ASH2L [nucleoplasm] (Xenopus tropicalis)
        
        H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        Core MLL complex [nucleoplasm] (Xenopus tropicalis)
        
        ASH2L [nucleoplasm] (Xenopus tropicalis)
        
        H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Xenopus tropicalis)
        
        Core MLL complex [nucleoplasm] (Xenopus tropicalis)
        
        ASH2L [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F7B5C3

Reference Genes

ENSEMBL:ENSXETG00000009007

Other Identifiers

AAMC01015685

AAMC01015686

ash2l-201

ENSXETG00000009007

ENSXETP00000019725

ENSXETT00000019725

GO:0002244

GO:0002376

GO:0003674

GO:0003677

GO:0005515

GO:0005575

GO:0006351

GO:0006464

GO:0008168

GO:0009058

GO:0030154

GO:0032991

GO:0034641

GO:0042592

GO:0042800

GO:0044212

GO:0048188

GO:0048856

GO:0051568

GO:0060319

IPR001870

IPR003877

IPR013320

IPR037353

SM00449

Str.8406.1.S1_at

UPI0002069007

XB-GENE-923264

Participant Of

hasComponent

input

Recruitment of SET1 methyltransferase complex

Inferred From

ASH2L [nucleoplasm] (Homo sapiens)