Reactome | socs2 [cytosol]

socs2 [cytosol]

Stable Identifier

R-XTR-1169204

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

SOCS2, B2WUN6

Locations in the PathwayBrowser

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Metabolism of proteins (Xenopus tropicalis)

- Post-translational protein modification (Xenopus tropicalis)
  - Neddylation (Xenopus tropicalis)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Xenopus tropicalis)
        
        CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        socs2 [cytosol] (Xenopus tropicalis)
      - CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        socs2 [cytosol] (Xenopus tropicalis)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Xenopus tropicalis)
        
        CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        socs2 [cytosol] (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        socs2 [cytosol] (Xenopus tropicalis)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        socs2 [cytosol] (Xenopus tropicalis)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        socs2 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:B2WUN6

Gene Names

socs2

Reference Genes

BioGPS Gene:100151723 socs2

ENSEMBL:ENSXETG00000042155

KEGG Gene (Xenopus tropicalis):100151723 socs2

Monarch:100151723 socs2

NCBI Gene:100151723 socs2

Reference Transcript

Other Identifiers

100151723

GO:0009968

GO:0016567

GO:0023052

GO:0035556

GO:0036211

Participates

as a member of

CUL5-box protein [cytosol] (Xenopus tropicalis)

Inferred From

SOCS2 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_012814072.1, NP_001120898.1, XP_031753518.1

Xenbase

XB-GENE-487261

Ensembl

ENSXETT00000112290, ENSXETG00000042155, ENSXETP00000111314

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