Expression of pax3 in the neural border

Stable Identifier
R-XLA-9835813
Type
Reaction [omitted]
Species
Xenopus laevis
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of pax3 in the neural border
Tfap2a activates expression of pax3 in the neural plate border (de Croze et al. 2011). Gbx2 is expressed prior to pax3 and activates expression of pax3 (Li et al. 2009).
Literature References
PubMed ID Title Journal Year
21169220 Reiterative AP2a activity controls sequential steps in the neural crest gene regulatory network

Maczkowiak, F, de Crozé, N, Monsoro-Burq, AH

Proc Natl Acad Sci U S A 2011
19736322 The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction

Moreno, M, Mayor, R, Kuriyama, S, Li, B

Development 2009
Participants
Input
Output
This event is regulated
Positively by
Regulator
gbx2 [nucleoplasm] (Xenopus laevis)
Regulator
tfap2a:pax3 gene [nucleoplasm] (Xenopus laevis)
Active Unit
pax3-a [nucleoplasm]
Orthologous Events
Expression of PAX3 in the neural plate border (Homo sapiens)
Authored
May, B  (2023-05-17)
Reviewed
Patthey, C  (2023-10-28)
Gunhaga, L  (2023-10-28)
Created
May, B  (2023-05-18)
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