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tfap2a binds the pax3 gene
Stable Identifier
R-XLA-9835799
Type
Reaction [binding]
Species
Xenopus laevis
Compartment
nucleoplasm
ReviewStatus
5/5
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
SVG
|
PNG
Low
Medium
High
|
PPTX
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SBGN
Tfap2a binds the promoter of the pax3 gene upstream of the pax3 coding region (de Croze et al. 2011). Tfap2a appears to mediate Wnt signals to initiate expression of pax3 in the neural plate border and subsequently regulates gene expression during specification of the neural crest (de Crose et al. 2011).
Literature References
PubMed ID
Title
Journal
Year
21169220
Reiterative AP2a activity controls sequential steps in the neural crest gene regulatory network
Maczkowiak, F
,
de Crozé, N
,
Monsoro-Burq, AH
Proc Natl Acad Sci U S A
2011
Participants
Input
pax3.S gene [nucleoplasm]
(Xenopus laevis)
tfap2a.S [nucleoplasm]
(Xenopus laevis)
Output
tfap2a:pax3 gene [nucleoplasm]
(Xenopus laevis)
Orthologous Events
TFAP2A binds the PAX3 gene (Homo sapiens)
Authored
May, B (2023-05-17)
Reviewed
Patthey, C (2023-10-28)
Gunhaga, L (2023-10-28)
Created
May, B (2023-05-18)
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