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K63polyUb-IKBKE:K63polyUb-TANK:K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
Stable Identifier
R-SSC-9823938
Type
Complex
Species
Sus scrofa
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Innate Immune System (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Sus scrofa)
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 (Sus scrofa)
IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Sus scrofa)
K63polyUb-IKBKE:K63polyUb-TANK:K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
K63polyUb-K30,K401-IKBKE homodimer [cytosol]
(Sus scrofa)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
(Sus scrofa)
Participates
as an output of
IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Sus scrofa)
Inferred From
K63polyUb-IKBKE:K63polyUb-TANK:K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
(Homo sapiens)
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