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E3 ligases in proteasomal degradation [cytosol]
Stable Identifier
R-SSC-976075
Type
Set [CandidateSet]
Species
Sus scrofa
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Class I MHC mediated antigen processing & presentation (Sus scrofa)
Antigen processing: Ubiquitination & Proteasome degradation (Sus scrofa)
Interaction of E3 with substrate and E2-Ub complex (Sus scrofa)
Ag-substrate:E3:E2:Ub [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
Polyubiquitination of substrate (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
E3:K48-polyubiquitinated substrate [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
E3:Ub:substrate [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
Release of E3 from polyubiquitinated substrate (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
E3:K48-polyubiquitinated substrate [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
Transfer of Ub from E2 to substrate and release of E2 (Sus scrofa)
Ag-substrate:E3:E2:Ub [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
E3:Ub:substrate [cytosol] (Sus scrofa)
E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)
Participants
members
CUL1 [cytosol] (Sus scrofa)
RNF144B [cytosol] (Sus scrofa)
RNF19B [cytosol] (Sus scrofa)
MIB2 [cytosol] (Sus scrofa)
NEDD4L [cytosol] (Sus scrofa)
SIAH1 [cytosol] (Sus scrofa)
SPSB1 [cytosol] (Sus scrofa)
TRIP12 [cytosol] (Sus scrofa)
DTX3L [cytosol] (Sus scrofa)
HERC5 [cytosol] (Sus scrofa)
RBCK1 [cytosol] (Sus scrofa)
SIAH2 [cytosol] (Sus scrofa)
TRIM21 [cytosol] (Sus scrofa)
TRIM69 [cytosol] (Sus scrofa)
UBR2 [cytosol] (Sus scrofa)
HUWE1 [cytosol] (Sus scrofa)
SMURF2 [cytosol] (Sus scrofa)
TRIM36 [cytosol] (Sus scrofa)
WSB1 [cytosol] (Sus scrofa)
SCF E3 ubiquitin ligase [cytosol] (Sus scrofa)
RNF213 [cytosol] (Sus scrofa)
HECTD2 [cytosol] (Sus scrofa)
LONRF1 [cytosol] (Sus scrofa)
RBBP6 [cytosol] (Sus scrofa)
RNF19A [cytosol] (Sus scrofa)
ZNRF1 [cytosol] (Sus scrofa)
HERC6 [cytosol] (Sus scrofa)
RNF217 [cytosol] (Sus scrofa)
Homologues of RNF114 [cytosol] (Sus scrofa)
ZNRF2 [cytosol] (Sus scrofa)
FBXL4 [cytosol] (Sus scrofa)
RLIM [cytosol] (Sus scrofa)
RNF115 [cytosol] (Sus scrofa)
UNKL [cytosol] (Sus scrofa)
MYLIP [cytosol] (Sus scrofa)
candidates
CBLB [cytosol] (Sus scrofa)
STUB1 [cytosol] (Sus scrofa)
DZIP3 [cytosol] (Sus scrofa)
HERC2 [cytosol] (Sus scrofa)
ITCH [cytosol] (Sus scrofa)
LRSAM1 [cytosol] (Sus scrofa)
MGRN1 [cytosol] (Sus scrofa)
NEDD4 [cytosol] (Sus scrofa)
RNF182 [cytosol] (Sus scrofa)
RNF220 [cytosol] (Sus scrofa)
RNF25 [cytosol] (Sus scrofa)
RNF6 [cytosol] (Sus scrofa)
SMURF1 [cytosol] (Sus scrofa)
TRIM11 [cytosol] (Sus scrofa)
TRIM32 [cytosol] (Sus scrofa)
TRIM37 [cytosol] (Sus scrofa)
TRIM63 [cytosol] (Sus scrofa)
TRIM9 [cytosol] (Sus scrofa)
UBR1 [cytosol] (Sus scrofa)
GAN [cytosol] (Sus scrofa)
WWP1 [cytosol] (Sus scrofa)
RCHY1 [cytosol] (Sus scrofa)
SPSB2 [cytosol] (Sus scrofa)
SPSB4 [cytosol] (Sus scrofa)
UBOX5 [cytosol] (Sus scrofa)
ATP5MG [cytosol] (Sus scrofa)
UBE3A [cytosol] (Sus scrofa)
UBE3B [cytosol] (Sus scrofa)
UBE3C [cytosol] (Sus scrofa)
RBX1-CUL2-EloB,C-VHL [cytosol] (Sus scrofa)
RBX1:CUL3:BTB [cytosol] (Sus scrofa)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Sus scrofa)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Sus scrofa)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Sus scrofa)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Sus scrofa)
APC/C E3 ligase complex [cytosol] (Sus scrofa)
UBR4 [cytosol] (Sus scrofa)
LRRC41 [cytosol] (Sus scrofa)
RNF41 [cytosol] (Sus scrofa)
PJA2 [cytosol] (Sus scrofa)
RNF123 [cytosol] (Sus scrofa)
PJA1 [cytosol] (Sus scrofa)
RNF34 [cytosol] (Sus scrofa)
FBXO27 [cytosol] (Sus scrofa)
FBXO44 [cytosol] (Sus scrofa)
RNF4 [cytosol] (Sus scrofa)
ARIH2 [cytosol] (Sus scrofa)
RNF138 [cytosol] (Sus scrofa)
Homologues of MKRN1 [cytosol] (Sus scrofa)
LRR1 [cytosol] (Sus scrofa)
RNF111 [cytosol] (Sus scrofa)
VPRBP [cytosol] (Sus scrofa)
DET1 [cytosol] (Sus scrofa)
LTN1 [cytosol] (Sus scrofa)
RNF14 [cytosol] (Sus scrofa)
SH3RF1 [cytosol] (Sus scrofa)
TRAF7 [cytosol] (Sus scrofa)
TRIM39 [cytosol] (Sus scrofa)
TRIM41 [cytosol] (Sus scrofa)
TRIM50 [cytosol] (Sus scrofa)
TRIM71 [cytosol] (Sus scrofa)
UFL1 [cytosol] (Sus scrofa)
AREL1 [cytosol] (Sus scrofa)
BTBD1 [cytosol] (Sus scrofa)
HACE1 [cytosol] (Sus scrofa)
HECW2 [cytosol] (Sus scrofa)
HERC1 [cytosol] (Sus scrofa)
HERC3 [cytosol] (Sus scrofa)
HERC4 [cytosol] (Sus scrofa)
KLHL11 [cytosol] (Sus scrofa)
LNX1 [cytosol] (Sus scrofa)
MEX3C [cytosol] (Sus scrofa)
RNF126 [cytosol] (Sus scrofa)
TBC1D9B [cytosol] (Sus scrofa)
TRAIP [cytosol] (Sus scrofa)
TRIM4 [cytosol] (Sus scrofa)
UBAC1 [cytosol] (Sus scrofa)
UBE3D [cytosol] (Sus scrofa)
ZNF645 [cytosol] (Sus scrofa)
Participant Of
hasComponent
Ag-substrate:E3:E2:Ub [cytosol]
E3:K48-polyubiquitinated substrate [cytosol]
E3:Ub:substrate [cytosol]
input
Interaction of E3 with substrate and E2-Ub complex
output
Release of E3 from polyubiquitinated substrate
Inferred From
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
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