Reactome | FBXO44 [cytosol]

FBXO44 [cytosol]

Stable Identifier

R-SSC-976031

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

FBXO44, A0A287A075

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Neddylation (Sus scrofa)
    - AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Sus scrofa)
      - CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Sus scrofa)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        SCF E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        F-box protein [cytosol] (Sus scrofa)
        
        FBXO44 [cytosol] (Sus scrofa)
      - NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        SCF E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        F-box protein [cytosol] (Sus scrofa)
        
        FBXO44 [cytosol] (Sus scrofa)
      - NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        NEDD8-CRL1 E3 ligase complex [cytosol] (Sus scrofa)
        
        F-box protein [cytosol] (Sus scrofa)
        
        FBXO44 [cytosol] (Sus scrofa)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Sus scrofa)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Sus scrofa)
        
        CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        SCF E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        F-box protein [cytosol] (Sus scrofa)
        
        FBXO44 [cytosol] (Sus scrofa)
      - CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        SCF E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        F-box protein [cytosol] (Sus scrofa)
        
        FBXO44 [cytosol] (Sus scrofa)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Sus scrofa)
        
        CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        SCF E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        F-box protein [cytosol] (Sus scrofa)
        
        FBXO44 [cytosol] (Sus scrofa)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        SCF E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        F-box protein [cytosol] (Sus scrofa)
        
        FBXO44 [cytosol] (Sus scrofa)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        SCF E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        F-box protein [cytosol] (Sus scrofa)
        
        FBXO44 [cytosol] (Sus scrofa)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        NEDD8-CRL1 E3 ligase complex [cytosol] (Sus scrofa)
        
        F-box protein [cytosol] (Sus scrofa)
        
        FBXO44 [cytosol] (Sus scrofa)
    - MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Sus scrofa)
      - CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Sus scrofa)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        SCF E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        F-box protein [cytosol] (Sus scrofa)
        
        FBXO44 [cytosol] (Sus scrofa)
      - CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        SCF E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        F-box protein [cytosol] (Sus scrofa)
        
        FBXO44 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287A075

Gene Names

FBXO44

Reference Genes

BioGPS Gene:100736592 FBXO44

ENSEMBL:ENSSSCG00000003421.5

Monarch:100736592 FBXO44

NCBI Entrez Gene:100736592 FBXO44

UCSC:A0A287A075 FBXO44

Reference Transcript

Other Identifiers

100736592

GO:0003824

GO:0005515

GO:0005737

GO:0006516

GO:0016740

GO:0019005

GO:0030163

GO:0031146

GO:0036503

GO:0061630

GO:0140096

GO:1901135

Ssc.20747.1.S1_at

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Sus scrofa)

as a member of

F-box protein [cytosol] (Sus scrofa)

Inferred From

FBXO44 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_020950995.1, XP_013854434.1

ENSEMBL

ENSSSCP00000037344, ENSSSCT00000056086, ENSSSCG00000003421

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