Reactome | KCNJ2 [plasma membrane]

KCNJ2 [plasma membrane]

Stable Identifier

R-SSC-975378

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

KCNJ2, O18839

Locations in the PathwayBrowser

Expand all

Neuronal System (Sus scrofa)

- Potassium Channels (Sus scrofa)
  - Inwardly rectifying K+ channels (Sus scrofa)
    - Classical Kir channels (Sus scrofa)
      - KCNJs transport K+ from the extracellular region to cytosol (Sus scrofa)
        
        KCNJ tetramer [plasma membrane] (Sus scrofa)
        
        KCNJs [plasma membrane] (Sus scrofa)
        
        KCNJ2 [plasma membrane] (Sus scrofa)
    - G protein gated Potassium channels (Sus scrofa)
      - Activation of G protein gated Potassium channels (Sus scrofa)
        
        Activation of GIRK/Kir3 Channels (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Sus scrofa)
        
        Kir heterotetramers [plasma membrane] (Sus scrofa)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Sus scrofa)
        
        KCNJ2 [plasma membrane] (Sus scrofa)
        
        Kir heterotetramers [plasma membrane] (Sus scrofa)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Sus scrofa)
        
        KCNJ2 [plasma membrane] (Sus scrofa)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Sus scrofa)
        
        Kir heterotetramers [plasma membrane] (Sus scrofa)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Sus scrofa)
        
        KCNJ2 [plasma membrane] (Sus scrofa)
        
        Kir heterotetramers [plasma membrane] (Sus scrofa)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Sus scrofa)
        
        KCNJ2 [plasma membrane] (Sus scrofa)
- Transmission across Chemical Synapses (Sus scrofa)
  - Neurotransmitter receptors and postsynaptic signal transmission (Sus scrofa)
    - GABA receptor activation (Sus scrofa)
      - GABA B receptor activation (Sus scrofa)
        
        Activation of GABAB receptors (Sus scrofa)
        
        Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (Sus scrofa)
        
        Activation of GIRK/Kir3 Channels (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Sus scrofa)
        
        Kir heterotetramers [plasma membrane] (Sus scrofa)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Sus scrofa)
        
        KCNJ2 [plasma membrane] (Sus scrofa)
        
        Kir heterotetramers [plasma membrane] (Sus scrofa)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Sus scrofa)
        
        KCNJ2 [plasma membrane] (Sus scrofa)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Sus scrofa)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Sus scrofa)
        
        Kir heterotetramers [plasma membrane] (Sus scrofa)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Sus scrofa)
        
        KCNJ2 [plasma membrane] (Sus scrofa)
        
        Kir heterotetramers [plasma membrane] (Sus scrofa)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Sus scrofa)
        
        KCNJ2 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:O18839

Gene Names

KCNJ2

Reference Genes

BioGPS Gene:397293 KCNJ2

ENSEMBL:ENSSSCG00000039947.3 KCNJ2

ENSEMBL:ENSSSCG00005005397.1 KCNJ2

ENSEMBL:ENSSSCG00015051436.1 KCNJ2

ENSEMBL:ENSSSCG00025027512.1

ENSEMBL:ENSSSCG00030002485.1 KCNJ2

ENSEMBL:ENSSSCG00035023144.1 KCNJ2

ENSEMBL:ENSSSCG00040011705.1 KCNJ2

ENSEMBL:ENSSSCG00045008402.1 KCNJ2

ENSEMBL:ENSSSCG00050003450.1 KCNJ2

ENSEMBL:ENSSSCG00055010394.1 KCNJ2

ENSEMBL:ENSSSCG00060040773.1 KCNJ2

ENSEMBL:ENSSSCG00065054903.1 KCNJ2

ENSEMBL:ENSSSCG00070002227.1 KCNJ2

KEGG Gene (Sus scrofa):397293 KCNJ2

Monarch:397293 KCNJ2

NCBI Gene:397293 KCNJ2

Reference Transcript

RefSeq:NM_214151.1 KCNJ2

Other Identifiers

397293

GO:0003012

GO:0003013

GO:0005215

GO:0005242

GO:0005546

GO:0005886

GO:0006813

GO:0008076

GO:0008289

GO:0014861

GO:0015693

GO:0016020

GO:0042802

GO:0050877

GO:0051289

GO:0055085

GO:0055119

GO:0060306

GO:0065003

GO:0071805

GO:0086001

GO:0086002

GO:0086008

GO:0086011

GO:0086013

GO:0086091

GO:0090076

GO:1990573

Ssc.15965.1.S1_at

Participates

as a member of

KCNJs [plasma membrane] (Sus scrofa)

as a component of

Kir2.1:Kirx.x heterotetramer [plasma membrane] (Sus scrofa)

Inferred From

KCNJ2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_999316.1

OpenTargets

ENSG00000123700

Ensembl

ENSSSCP00000058999, ENSSSCG00000039947, ENSSSCP00000043274, ENSSSCT00000061811, ENSSSCT00000050128

VGNC

89357