Reactome | activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane]

activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane]

Stable Identifier

R-SSC-9657583

Type

Complex

Species

Sus scrofa

Compartment

plasma membrane

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
dual mechanism MAP2K1/2 inhibitors [cytosol]

Participates

as an output of

Dual mechanism MAP2K inhibitors bind MAP2Ks (Sus scrofa)

This entity regulates

Negatively

MAP2Ks phosphorylate MAPKs (Sus scrofa)
RAF phosphorylates MAP2K dimer (Sus scrofa)

Inferred From

activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Homo sapiens)

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