Reactome | MCHR1 [plasma membrane]

MCHR1 [plasma membrane]

Stable Identifier

R-SSC-947682

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

F1SRB6

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (i) signalling events (Sus scrofa)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
      - The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
    - G alpha (q) signalling events (Sus scrofa)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
      - The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
        
        GPCRs that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        Melanin-concentrating hormone receptors bind MCH (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Sus scrofa)
        
        MCHR1,MCHR2 [plasma membrane] (Sus scrofa)
        
        MCHR1 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SRB6

Reference Genes

BioGPS Gene:397295

ENSEMBL:ENSSSCG00000000074.5

KEGG Gene (Sus scrofa):397295

Monarch:397295

NCBI Gene:397295

Reference Transcript

RefSeq:NM_001008684.1

Other Identifiers

397295

GO:0004930

GO:0005102

GO:0005886

GO:0005929

GO:0007165

GO:0007186

GO:0007218

GO:0016020

GO:0023052

GO:0030273

GO:0042923

GO:0043005

GO:0043226

GO:0060089

GO:0060170

GO:0097730

Ssc.15970.1.S1_at

Participates

as a candidate of

BBSome ciliary cargo [plasma membrane] (Sus scrofa)

as a member of

MCHR1,MCHR2 [plasma membrane] (Sus scrofa)

Other forms of this molecule

MCHR1 [ciliary membrane]

Inferred From

MCHR1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001008684.1

Ensembl

ENSSSCP00000000079, ENSSSCG00000000074, ENSSSCT00000000080

VGNC

103300

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