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activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane]
Stable Identifier
R-SSC-936970
Type
Set [DefinedSet]
Species
Sus scrofa
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Innate Immune System (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Sus scrofa)
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Sus scrofa)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Sus scrofa)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Sus scrofa)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Sus scrofa)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Sus scrofa)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Sus scrofa)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Sus scrofa)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Sus scrofa)
Participants
members
p-S172-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
(Sus scrofa)
p-S172-IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
(Sus scrofa)
Participates
as an output of
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Sus scrofa)
as an input of
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Sus scrofa)
as a component of
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Sus scrofa)
Inferred From
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane]
(Homo sapiens)
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