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holoTF:TFRC dimer [plasma membrane]
Stable Identifier
R-SSC-917834
Type
Complex
Species
Sus scrofa
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Sus scrofa)
Iron uptake and transport (Sus scrofa)
Transferrin endocytosis and recycling (Sus scrofa)
TFRC dimer binds 2xholoTF (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer translocates from plasma membrane to endosome membrane (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
Vesicle-mediated transport (Sus scrofa)
Membrane Trafficking (Sus scrofa)
Clathrin-mediated endocytosis (Sus scrofa)
BAR domain proteins recruit dynamin (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
Cargo recognition for clathrin-mediated endocytosis (Sus scrofa)
AP-2 directly binds some endocytic cargo (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
Clathrin recruits PIK3C2A (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
Endophilins recruit synaptojanins to the clathrin-coated pit (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
F- and N- BAR domain proteins bind the clathrin-coated pit (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
SNX9 recruits components of the actin polymerizing machinery (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
CLASP proteins:cargo [plasma membrane] (Sus scrofa)
AP-2:cargo [plasma membrane] (Sus scrofa)
AP-2 cargo [plasma membrane] (Sus scrofa)
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
holoTF:TFRC dimer [plasma membrane] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
holoTF [extracellular region]
(Sus scrofa)
TFRC dimer [plasma membrane]
(Sus scrofa)
Participates
as a member of
AP-2 YXXPhi cargo [plasma membrane] (Sus scrofa)
as an output of
TFRC dimer binds 2xholoTF (Sus scrofa)
as an input of
holoTF:TFRC dimer translocates from plasma membrane to endosome membrane (Sus scrofa)
Inferred From
holoTF:TFRC dimer [plasma membrane]
(Homo sapiens)
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