Reactome | GPHA2 [extracellular region]

GPHA2 [extracellular region]

Stable Identifier

R-SSC-8942422

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

extracellular region

Synonyms

GPHA2, F1RQR6

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (s) signalling events (Sus scrofa)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Sus scrofa)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Sus scrofa)
        
        TSHR:Thyrotropin [plasma membrane] (Sus scrofa)
        
        Thyrostimulin [extracellular region] (Sus scrofa)
        
        GPHA2 [extracellular region] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Sus scrofa)
        
        TSHR:Thyrotropin [plasma membrane] (Sus scrofa)
        
        Thyrostimulin [extracellular region] (Sus scrofa)
        
        GPHA2 [extracellular region] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Hormone ligand-binding receptors (Sus scrofa)
        
        Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin (Sus scrofa)
        
        TSHR:Thyrotropin [plasma membrane] (Sus scrofa)
        
        Thyrostimulin [extracellular region] (Sus scrofa)
        
        GPHA2 [extracellular region] (Sus scrofa)
        
        Thyrostimulin [extracellular region] (Sus scrofa)
        
        GPHA2 [extracellular region] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RQR6

Gene Names

GPHA2

Reference Genes

ENSEMBL:ENSSSCG00000013015

Reference Transcript

RefSeq:XM_013994132.1 GPHA2

Other Identifiers

100516058

GO:0003674

GO:0005179

GO:0005575

GO:0005576

GO:0005615

GO:0007165

GO:0007166

GO:0007189

GO:0008150

GO:0031531

GO:0046982

GO:0051427

Participant Of

hasComponent

Thyrostimulin [extracellular region]

Inferred From

GPHA2 [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_013849586.1

OpenTargets

ENSG00000149735

Ensembl

ENSSSCG00000013015, ENSSSCP00000013840, ENSSSCT00000014226

VGNC

88585

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