Reactome | VAMP8 [clathrin-coated endocytic vesicle membrane]

VAMP8 [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-SSC-8869137

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

I3LHS5

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - Clathrin-mediated endocytosis (Sus scrofa)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PICALM:VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PICALM:VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PICALM:VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PICALM:VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PICALM:VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PICALM:VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PICALM:VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        VAMP8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:I3LHS5

Reference Genes

ENSEMBL:ENSSSCG00000022820

Other Identifiers

GO:0003674

GO:0005484

GO:0005575

GO:0005622

GO:0005737

GO:0005886

GO:0006810

GO:0006906

GO:0008150

GO:0016020

GO:0016021

GO:0016192

GO:0019905

GO:0022607

GO:0030674

GO:0031201

GO:0031410

GO:0032991

GO:0035493

GO:0043226

GO:0061024

GO:0065003

GO:0070254

GO:0098594

Ssc.1171.1.S1_at

Participates

as a member of

VAMP2,3,8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)

Other forms of this molecule

VAMP8 [secretory granule membrane]

VAMP8 [cytoplasmic vesicle membrane]

VAMP8 [Golgi membrane]

VAMP8 [lysosomal membrane]

VAMP8 [phagocytic vesicle membrane]

VAMP8 [recycling endosome membrane]

VAMP8 [azurophil granule membrane]

VAMP8 [specific granule membrane]

VAMP8 [plasma membrane]

VAMP8 [tertiary granule membrane]

Inferred From

VAMP8 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

Ensembl

ENSSSCG00000022820, ENSSSCT00000029311, ENSSSCP00000023622

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