Reactome | SLC2A8 [clathrin-coated endocytic vesicle membrane]

SLC2A8 [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-SSC-8869111

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

SLC2A8, F1RS19

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - Clathrin-mediated endocytosis (Sus scrofa)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        SLC2A8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        SLC2A8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        SLC2A8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        SLC2A8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        SLC2A8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        SLC2A8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        SLC2A8 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RS19

Gene Names

SLC2A8

Reference Genes

BioGPS Gene:100125551 SLC2A8

ENSEMBL:ENSSSCG00000005610

Monarch:100125551 SLC2A8

NCBI Gene:100125551 SLC2A8

Reference Transcript

RefSeq:XM_005660438.2 SLC2A8

Other Identifiers

100125551

GO:0003674

GO:0005575

GO:0005886

GO:0006810

GO:0008150

GO:0008643

GO:0016020

GO:0016021

GO:0022857

GO:0055085

Ssc.12400.1.S1_at

Participant Of

hasMember

AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane]

Other forms of this molecule

SLC2A8 [plasma membrane]

Inferred From

SLC2A8 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

XP_005660495.1

OpenTargets

ENSG00000136856

Ensembl

ENSSSCG00000005610, ENSSSCT00000006169, ENSSSCP00000006010

VGNC

93053

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