Reactome | AVP [clathrin-coated endocytic vesicle membrane]

AVP [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-SSC-8869075

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

AVP(20-28), P01183

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - Clathrin-mediated endocytosis (Sus scrofa)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - RAB5 and GAPVD1 bind AP-2 (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:P01183

Gene Names

AVP

Reference Genes

BioGPS Gene:396995 AVP

ENSEMBL:ENSSSCG00025044667.1 AVP

ENSEMBL:ENSSSCG00030035426.1

ENSEMBL:ENSSSCG00035042676.1 AVP

ENSEMBL:ENSSSCG00040028620.1 AVP

ENSEMBL:ENSSSCG00045002408.1 AVP

ENSEMBL:ENSSSCG00050058482.1 AVP

ENSEMBL:ENSSSCG00060011180.1 AVP

ENSEMBL:ENSSSCG00065063862.1 AVP

KEGG Gene (Sus scrofa):396995 AVP

Monarch:396995 AVP

NCBI Gene:396995 AVP

Reference Transcript

RefSeq:NM_213952.2 AVP

Participates

as a component of

AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Sus scrofa)

Other forms of this molecule

AVP [cytosol]

AVP [extracellular region]

Inferred From

AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_999117.1

OpenTargets

ENSG00000101200

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