Reactome | SNAPC2 [nucleoplasm]

SNAPC2 [nucleoplasm]

Stable Identifier

R-SSC-83725

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

F1SA68

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - RNA polymerase II transcribes snRNA genes (Sus scrofa)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
    - Integrator complex processes the 3' end of snRNA (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Sus scrofa)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Sus scrofa)
        
        SNAPc [nucleoplasm] (Sus scrofa)
        
        SNAPC2 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SA68

Reference Genes

BioGPS Gene:100520776

ENSEMBL:ENSSSCG00000013589

KEGG Gene (Sus scrofa):100520776

Monarch:100520776

NCBI Gene:100520776

Reference Transcript

RefSeq:XM_003123198.3

Other Identifiers

100520776

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0016604

GO:0043226

Ssc.4866.1.S1_at

Participates

as a component of

SNAPc [nucleoplasm] (Sus scrofa)

Inferred From

SNAPC2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_003123246.1

Ensembl

ENSSSCG00000013589, ENSSSCP00000014440, ENSSSCT00000014841

VGNC

93281

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