Reactome | PIK3R1 [cytosol]

PIK3R1 [cytosol]

Stable Identifier

R-SSC-74789

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

PIK3R1, F1SKR9

Locations in the PathwayBrowser

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Developmental Biology (Sus scrofa)

- Nervous system development (Sus scrofa)
  - Axon guidance (Sus scrofa)
    - RET signaling (Sus scrofa)
      - p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Sus scrofa)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)

Immune System (Sus scrofa)

- Adaptive Immune System (Sus scrofa)
  - Costimulation by the CD28 family (Sus scrofa)
    - CD28 co-stimulation (Sus scrofa)
      - CD28 dependent PI3K/Akt signaling (Sus scrofa)
        
        CD28 bound PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
        
        CD28:PI3K [plasma membrane] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K binds CD28 (Sus scrofa)
        
        CD28:PI3K [plasma membrane] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
    - PI3K binds ICOS (Sus scrofa)
      - ICOS:PI3K [plasma membrane] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
      - PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
  - Signaling by the B Cell Receptor (BCR) (Sus scrofa)
    - Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Sus scrofa)
      - p-CD19:VAV binds PI3K and GRB2 (Sus scrofa)
        
        PIK3CD:PIK3R1 [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
  - TCR signaling (Sus scrofa)
    - Downstream TCR signaling (Sus scrofa)
      - PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Sus scrofa)
        
        PI3K bound to TRAT [plasma membrane] (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
      - Recruitment of PI3K to plasma membrane (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K bound to TRAT [plasma membrane] (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
- Cytokine Signaling in Immune system (Sus scrofa)
  - FLT3 Signaling (Sus scrofa)
    - Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Sus scrofa)
      - Active FLT3:GRB2:p-Y GAB2:PI3K [plasma membrane] (Sus scrofa)
        
        Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
      - Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
    - Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Sus scrofa)
      - active FLT3:p-Y GRB10:PI3K [plasma membrane] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
      - active FLT3:p-Y GRB10:PIK3R1 [plasma membrane] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
    - Active FLT3:p-Y-GRB10 binds PIK3R1 (Sus scrofa)
      - PIK3R1 [cytosol] (Sus scrofa)
      - active FLT3:p-Y GRB10:PIK3R1 [plasma membrane] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
  - Signaling by Interleukins (Sus scrofa)
    - Interleukin-2 family signaling (Sus scrofa)
      - Interleukin receptor SHC signaling (Sus scrofa)
        
        Gab2 binds the p85 subunit of Class 1A PI3 kinases (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
    - Interleukin-3, Interleukin-5 and GM-CSF signaling (Sus scrofa)
      - 14-3-3 zeta binding allows recruitment of PI3K (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
      - Interleukin receptor SHC signaling (Sus scrofa)
        
        Gab2 binds the p85 subunit of Class 1A PI3 kinases (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
      - Regulation of signaling by CBL (Sus scrofa)
        
        CBL ubiquitinates PI3K (Sus scrofa)
        
        FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated (Sus scrofa)
        
        FYN-like kinases:CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        p85-containing Class 1A PI3Ks [cytosol] (Sus scrofa)
        
        PI3K alpha [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K beta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K delta [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
    - Interleukin-7 signaling (Sus scrofa)
      - IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Sus scrofa)
        
        IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits:IRS1,IRS2 [plasma membrane] (Sus scrofa)
        
        IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:JAK3:PI3K-regulatory subunits [plasma membrane] (Sus scrofa)
        
        PI3K regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:JAK3:PI3K-regulatory subunits [plasma membrane] (Sus scrofa)
        
        PI3K regulatory subunits [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
- Innate Immune System (Sus scrofa)
  - DAP12 interactions (Sus scrofa)
    - DAP12 signaling (Sus scrofa)
      - PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
        
        DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
      - p85 regulatory unit of PI3K binds p-6Y-SYK (Sus scrofa)
        
        DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
  - Fc epsilon receptor (FCERI) signaling (Sus scrofa)
    - Role of LAT2/NTAL/LAB on calcium mobilization (Sus scrofa)
      - PI3K associates with phosphorylated GAB2 (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
      - Phosphorylation of PIP2 to PIP3 by PI3K (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Sus scrofa)
    - Role of phospholipids in phagocytosis (Sus scrofa)
      - PI3K binds to p-6Y-SYK (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K:p-6Y-SYK [plasma membrane] (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
      - PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)
        
        PI3K:p-6Y-SYK [plasma membrane] (Sus scrofa)
        
        PI3K [cytosol] (Sus scrofa)
        
        PI3K-regulatory subunit [cytosol] (Sus scrofa)
        
        PIK3R1 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SKR9

Gene Names

PIK3R1

Reference Genes

BioGPS Gene:100623707 PIK3R1

ENSEMBL:ENSSSCG00000016958.6

KEGG Gene (Sus scrofa):100623707 PIK3R1

Monarch:100623707 PIK3R1

NCBI Gene:100623707 PIK3R1

Reference Transcript

RefSeq:XM_005672504.2 PIK3R1

Other Identifiers

100623707

GO:0001678

GO:0001784

GO:0001953

GO:0002376

GO:0002687

GO:0005158

GO:0005159

GO:0005168

GO:0005634

GO:0005737

GO:0005783

GO:0005794

GO:0005801

GO:0005829

GO:0005911

GO:0005943

GO:0006351

GO:0006355

GO:0006366

GO:0006606

GO:0006886

GO:0006913

GO:0007010

GO:0007155

GO:0007162

GO:0008286

GO:0008625

GO:0008630

GO:0010592

GO:0012501

GO:0016020

GO:0019209

GO:0019221

GO:0019903

GO:0023052

GO:0030154

GO:0030183

GO:0030316

GO:0032760

GO:0032869

GO:0033120

GO:0034143

GO:0034330

GO:0034644

GO:0034976

GO:0035655

GO:0036312

GO:0042307

GO:0043066

GO:0043125

GO:0043226

GO:0043491

GO:0043559

GO:0043560

GO:0045671

GO:0045944

GO:0046935

GO:0046982

GO:0048009

GO:0048471

GO:0048661

GO:0048856

GO:0048870

GO:0050821

GO:0051491

GO:0051492

GO:0051497

GO:0060396

GO:0072659

GO:0097529

GO:0098542

GO:0098772

GO:0120183

GO:1900103

GO:1903076

GO:1990578

Ssc.10754.1.A1_at

Ssc.13752.1.S1_at

Participates

as a candidate of

as a member of

as an input of

as a component of

Other forms of this molecule

PIK3R1 [cytosol]

PIK3R1 [plasma membrane]

Inferred From

PIK3R1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_005672561.1

OpenTargets

ENSG00000145675

Ensembl

ENSSSCP00000030884, ENSSSCT00000033882, ENSSSCG00000016958

VGNC

91445

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