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EIF4G1 [cytosol]
Stable Identifier
R-SSC-72584
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
EIF4G1, A0A287B9M9
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Interferon Signaling (Sus scrofa)
Antiviral mechanism by IFN-stimulated genes (Sus scrofa)
ISG15 antiviral mechanism (Sus scrofa)
Competitive inhibition of translation initiation by ISGylated 4EHP (Sus scrofa)
EIF4F [cytosol] (Sus scrofa)
EIF4G [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
eIF4F:mRNA [cytosol] (Sus scrofa)
EIF4F [cytosol] (Sus scrofa)
EIF4G [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Metabolism of RNA (Sus scrofa)
Deadenylation-dependent mRNA decay (Sus scrofa)
Deadenylation of mRNA (Sus scrofa)
CCR4-NOT complex deadenylates mRNA (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Partially Deadenylated mRNA Complex [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
PAN2-PAN3 complex partially deadenylates mRNA (Sus scrofa)
Partially Deadenylated mRNA Complex [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Translatable mRNA Complex [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
PARN deadenylates mRNA (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Partially Deadenylated mRNA Complex [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Nonsense-Mediated Decay (NMD) (Sus scrofa)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Sus scrofa)
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
mRNA Cleaved by SMG6 [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Sus scrofa)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
SMG6 hydrolyzes mRNA with premature termination codon (Sus scrofa)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
mRNA Cleaved by SMG6 [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Sus scrofa)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Sus scrofa)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Sus scrofa)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Sus scrofa)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Sus scrofa)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Sus scrofa)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Regulation of mRNA stability by proteins that bind AU-rich elements (Sus scrofa)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Sus scrofa)
AUF1 (hnRNP D0) is ubiquitinylated (Sus scrofa)
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
AUF1 binds translation and heat shock proteins (Sus scrofa)
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Translation (Sus scrofa)
Eukaryotic Translation Initiation (Sus scrofa)
Cap-dependent Translation Initiation (Sus scrofa)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Sus scrofa)
Translation initiation complex formation (Sus scrofa)
Formation of translation initiation complexes containing mRNA that does not circularize (Sus scrofa)
48S complex [cytosol] (Sus scrofa)
eIF4F [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
mRNA:eIF4F:eIF4B:eIF4H [cytosol] (Sus scrofa)
eIF4F [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Sus scrofa)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Sus scrofa)
eIF4F [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H [cytosol] (Sus scrofa)
eIF4F [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Ribosomal scanning and start codon recognition (Sus scrofa)
Ribosomal scanning (Sus scrofa)
48S complex [cytosol] (Sus scrofa)
eIF4F [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Start codon recognition (Sus scrofa)
48S complex [cytosol] (Sus scrofa)
eIF4F [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
L13a-mediated translational silencing of Ceruloplasmin expression (Sus scrofa)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Sus scrofa)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Sus scrofa)
eIF4F [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Sus scrofa)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Sus scrofa)
eIF4F [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
MTOR signalling (Sus scrofa)
mTORC1-mediated signalling (Sus scrofa)
Phosphorylation and activation of eIF4G by activated S6K1 (Sus scrofa)
EIF4G1 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A287B9M9
Gene Names
EIF4G1
Reference Genes
ENSEMBL:ENSSSCG00000030255.4
Other Identifiers
449528
GO:0000278
GO:0001662
GO:0003723
GO:0003729
GO:0003743
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005840
GO:0006412
GO:0006413
GO:0006446
GO:0006914
GO:0008135
GO:0008190
GO:0009059
GO:0010494
GO:0010507
GO:0010801
GO:0016281
GO:0030154
GO:0030182
GO:0030307
GO:0031047
GO:0031669
GO:0033138
GO:0034330
GO:0035278
GO:0036211
GO:0036493
GO:0042802
GO:0043226
GO:0045182
GO:0045666
GO:0048856
GO:0051247
GO:0065003
GO:0097009
GO:1900087
GO:1904377
GO:1905537
GO:1905606
Ssc.30760.1.S1_at
Participates
as an input of
AUF1 binds translation and heat shock proteins (Sus scrofa)
Phosphorylation and activation of eIF4G by activated S6K1 (Sus scrofa)
as a component of
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Sus scrofa)
mRNA Cleaved by SMG6 [cytosol] (Sus scrofa)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Sus scrofa)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Sus scrofa)
eIF4F [cytosol] (Sus scrofa)
Translatable mRNA Complex [cytosol] (Sus scrofa)
Partially Deadenylated mRNA Complex [cytosol] (Sus scrofa)
as an output of
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Sus scrofa)
PARN deadenylates mRNA (Sus scrofa)
CCR4-NOT complex deadenylates mRNA (Sus scrofa)
as a member of
EIF4G [cytosol] (Sus scrofa)
Other forms of this molecule
phospho-EIF4G1 [cytosol]
Inferred From
EIF4G1 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000114867
Ensembl
ENSSSCT00000049427
,
ENSSSCG00000030255
,
ENSSSCP00000052793
VGNC
87631
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