Reactome | Ghost homologue of mRNA [cytosol]

Immune System (Sus scrofa)

- Cytokine Signaling in Immune system (Sus scrofa)
  - Interferon Signaling (Sus scrofa)
    - Antiviral mechanism by IFN-stimulated genes (Sus scrofa)
      - ISG15 antiviral mechanism (Sus scrofa)
        
        Competitive inhibition of translation initiation by ISGylated 4EHP (Sus scrofa)
        
        ISGylated 4EHP:mRNA [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)
        
        eIF4F:mRNA [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)

Metabolism of RNA (Sus scrofa)

- Processing of Capped Intron-Containing Pre-mRNA (Sus scrofa)
  - Transport of Mature Transcript to Cytoplasm (Sus scrofa)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Sus scrofa)
      - Transport of the export-competent mRNP complex through the NPC (Sus scrofa)
        
        NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)
      - mRNP complex dissociates from cytosolic face of NPC (Sus scrofa)
        
        NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)
        
        mRNA:CBC:EJC:POLDIP3 [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)

Metabolism of proteins (Sus scrofa)

- Translation (Sus scrofa)
  - Eukaryotic Translation Initiation (Sus scrofa)
    - Cap-dependent Translation Initiation (Sus scrofa)
      - Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Sus scrofa)
        
        Translation initiation complex formation (Sus scrofa)
        
        Formation of translation initiation complexes containing mRNA that does not circularize (Sus scrofa)
        
        48S complex [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)
        
        mRNA:eIF4F:eIF4B:eIF4H [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)
      - GTP hydrolysis and joining of the 60S ribosomal subunit (Sus scrofa)
        
        The 60S subunit joins the translation initiation complex (Sus scrofa)
        
        40S:Met-tRNAi:mRNA [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)
        
        80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)
        
        eIF5B:GTP is hydrolyzed and released (Sus scrofa)
        
        80S:Met-tRNAi:mRNA [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)
        
        80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)
      - Ribosomal scanning and start codon recognition (Sus scrofa)
        
        Ribosomal scanning (Sus scrofa)
        
        48S complex [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)
        
        Start codon recognition (Sus scrofa)
        
        48S complex [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)
  - SRP-dependent cotranslational protein targeting to membrane (Sus scrofa)
    - Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Sus scrofa)
      - SRP:polypeptide+signal:ribosome [cytosol] (Sus scrofa)
        
        ribosome:mRNA:polypeptide+signal [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)
      - ribosome:mRNA:polypeptide+signal [cytosol] (Sus scrofa)
        
        Ghost homologue of mRNA [cytosol] (Sus scrofa)