Reactome | OGDH [mitochondrial matrix]

OGDH [mitochondrial matrix]

Stable Identifier

R-SSC-69981

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

mitochondrial matrix

Synonyms

OGDH, F1SSH8

Locations in the PathwayBrowser

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Metabolism (Sus scrofa)

- Aerobic respiration and respiratory electron transport (Sus scrofa)
  - Citric acid cycle (TCA cycle) (Sus scrofa)
    - OGDH complex synthesizes succinyl-CoA from 2-OG (Sus scrofa)
      - DLD dimer dehydrogenates dihydrolipoyl (Sus scrofa)
        
        OGDH complex [mitochondrial matrix] (Sus scrofa)
        
        OGDH dimer [mitochondrial matrix] (Sus scrofa)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Sus scrofa)
        
        OGDH [mitochondrial matrix] (Sus scrofa)
      - DLST transfers succinyl to CoA (Sus scrofa)
        
        OGDH complex [mitochondrial matrix] (Sus scrofa)
        
        OGDH dimer [mitochondrial matrix] (Sus scrofa)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Sus scrofa)
        
        OGDH [mitochondrial matrix] (Sus scrofa)
      - OGDH dimer decarboxylates 2-OG (Sus scrofa)
        
        OGDH complex [mitochondrial matrix] (Sus scrofa)
        
        OGDH dimer [mitochondrial matrix] (Sus scrofa)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Sus scrofa)
        
        OGDH [mitochondrial matrix] (Sus scrofa)
        
        OGDH dimer [mitochondrial matrix] (Sus scrofa)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Sus scrofa)
        
        OGDH [mitochondrial matrix] (Sus scrofa)
- Metabolism of amino acids and derivatives (Sus scrofa)
  - Glyoxylate metabolism and glycine degradation (Sus scrofa)
    - Glycine degradation (Sus scrofa)
      - DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Sus scrofa)
        
        OGDH complex [mitochondrial matrix] (Sus scrofa)
        
        OGDH dimer [mitochondrial matrix] (Sus scrofa)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Sus scrofa)
        
        OGDH [mitochondrial matrix] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SSH8

Gene Names

OGDH

Reference Genes

ENSEMBL:ENSSSCG00000016743.5

Other Identifiers

100515636

GO:0003824

GO:0004591

GO:0005634

GO:0005739

GO:0006091

GO:0006099

GO:0006103

GO:0006104

GO:0006790

GO:0016491

GO:0016624

GO:0021695

GO:0021756

GO:0021766

GO:0021794

GO:0021860

GO:0022028

GO:0030154

GO:0030976

GO:0034602

GO:0043226

GO:0045252

GO:0048856

GO:0048870

GO:0055086

GO:0061034

GO:1901135

Ssc.2345.1.S1_at

Participates

as a member of

as a component of

alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Sus scrofa)

Inferred From

OGDH [mitochondrial matrix] (Homo sapiens)

Cross References

OpenTargets

ENSG00000105953

Ensembl

ENSSSCG00000016743, ENSSSCP00000017733, ENSSSCT00000018225

VGNC

98168