Reactome | DSC2 [plasma membrane]

DSC2 [plasma membrane]

Stable Identifier

R-SSC-6814398

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

DSC2, A0A287A191

Locations in the PathwayBrowser

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Developmental Biology (Sus scrofa)

- Keratinization (Sus scrofa)
  - Formation of the cornified envelope (Sus scrofa)
    - Fillagrin and keratin intermediate filaments polymerize forming a network (Sus scrofa)
      - FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmocolins [plasma membrane] (Sus scrofa)
        
        DSC2 [plasma membrane] (Sus scrofa)
      - FLG-Keratin filament network [plasma membrane] (Sus scrofa)
        
        FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmocolins [plasma membrane] (Sus scrofa)
        
        DSC2 [plasma membrane] (Sus scrofa)
    - PERP binds desmosomes (Sus scrofa)
      - Desmosome [plasma membrane] (Sus scrofa)
        
        Desmocolins [plasma membrane] (Sus scrofa)
        
        DSC2 [plasma membrane] (Sus scrofa)
      - Desmosome:PERP [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmocolins [plasma membrane] (Sus scrofa)
        
        DSC2 [plasma membrane] (Sus scrofa)
    - Plasma membrane resorption (Sus scrofa)
      - Mature cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-cornified envelope:CDSN [plasma membrane] (Sus scrofa)
        
        No FGN-Cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-late cornified envelope [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome network [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmocolins [plasma membrane] (Sus scrofa)
        
        DSC2 [plasma membrane] (Sus scrofa)
  - Keratin filaments bind cell-cell adhesion complexes (Sus scrofa)
    - Desmosome [plasma membrane] (Sus scrofa)
      - Desmocolins [plasma membrane] (Sus scrofa)
        
        DSC2 [plasma membrane] (Sus scrofa)
    - Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
      - Desmosome [plasma membrane] (Sus scrofa)
        
        Desmocolins [plasma membrane] (Sus scrofa)
        
        DSC2 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287A191

Gene Names

DSC2

Reference Genes

ENSEMBL:ENSSSCG00000024800.4

Other Identifiers

100623651

GO:0003012

GO:0003013

GO:0005509

GO:0005783

GO:0005886

GO:0005912

GO:0007155

GO:0007156

GO:0009267

GO:0014704

GO:0016020

GO:0030057

GO:0031410

GO:0043226

GO:0070161

GO:0086042

GO:0086073

GO:0086091

GO:0098609

GO:0098911

Ssc.27369.1.A1_at

Participates

as a member of

Desmocolins [plasma membrane] (Sus scrofa)

Other forms of this molecule

DSC2 [cornified envelope]

Inferred From

DSC2 [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000134755

Ensembl

ENSSSCG00000024800, ENSSSCT00000048109, ENSSSCP00000037691

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