Reactome | KDELR2 [Golgi membrane]

KDELR2 [Golgi membrane]

Stable Identifier

R-SSC-6808784

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

Golgi membrane

Synonyms

KDELR2, A0A287A228

Locations in the PathwayBrowser

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Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Asparagine N-linked glycosylation (Sus scrofa)
    - Transport to the Golgi and subsequent modification (Sus scrofa)
      - ER to Golgi Anterograde Transport (Sus scrofa)
        
        COPI-mediated anterograde transport (Sus scrofa)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Sus scrofa)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Sus scrofa)
        
        KDELR2 [Golgi membrane] (Sus scrofa)
        
        cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Sus scrofa)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Sus scrofa)
        
        KDELR2 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Sus scrofa)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Sus scrofa)
        
        KDELR2 [Golgi membrane] (Sus scrofa)

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - ER to Golgi Anterograde Transport (Sus scrofa)
    - COPI-mediated anterograde transport (Sus scrofa)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Sus scrofa)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Sus scrofa)
        
        KDELR2 [Golgi membrane] (Sus scrofa)
      - cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Sus scrofa)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Sus scrofa)
        
        KDELR2 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Sus scrofa)
        
        ERGIC-to-cis-Golgi cargo [Golgi membrane] (Sus scrofa)
        
        KDELR2 [Golgi membrane] (Sus scrofa)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Sus scrofa)
    - Golgi-to-ER retrograde transport (Sus scrofa)
      - COPI-dependent Golgi-to-ER retrograde traffic (Sus scrofa)
        
        ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Sus scrofa)
        
        Golgi-to-ER cargo [Golgi membrane] (Sus scrofa)
        
        KDELR2 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Sus scrofa)
        
        Golgi-to-ER cargo [Golgi membrane] (Sus scrofa)
        
        KDELR2 [Golgi membrane] (Sus scrofa)
        
        ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Sus scrofa)
        
        RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Sus scrofa)
        
        Golgi-to-ER cargo [Golgi membrane] (Sus scrofa)
        
        KDELR2 [Golgi membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287A228

Gene Names

KDELR2

Reference Genes

ENSEMBL:ENSSSCG00000031432.3

Reference Transcript

RefSeq:XM_013991589.1 KDELR2

Other Identifiers

100625446

GO:0000139

GO:0005046

GO:0005783

GO:0005789

GO:0005794

GO:0006890

GO:0016192

GO:0030663

GO:0031410

GO:0035437

GO:0043226

Ssc.997.1.S1_at

Ssc.997.2.S1_at

Participates

as a member of

Golgi-to-ER cargo [Golgi membrane] (Sus scrofa)

as a candidate of

ERGIC-to-cis-Golgi cargo [Golgi membrane] (Sus scrofa)

Other forms of this molecule

KDELR2 [endoplasmic reticulum membrane]

KDELR2 [endoplasmic reticulum-Golgi intermediate compartment membrane]

KDELR2 [transport vesicle]

Inferred From

KDELR2 [Golgi membrane] (Homo sapiens)

Cross References

RefSeq

XP_013847043.1

OpenTargets

ENSG00000136240

Ensembl

ENSSSCP00000037780, ENSSSCG00000031432, ENSSSCT00000062901

VGNC

89405

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