Reactome | POM121C [nuclear envelope]

Cell Cycle (Sus scrofa)

- Cell Cycle, Mitotic (Sus scrofa)
  - M Phase (Sus scrofa)
    - Mitotic Prophase (Sus scrofa)
      - Nuclear Envelope Breakdown (Sus scrofa)
        
        Nuclear Pore Complex (NPC) Disassembly (Sus scrofa)
        
        CDK1 phosphorylates NUP98 (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        Nuclear Pore Complex (p-2S,3T-NUP98) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        NEK6/NEK7 phosphorylates NUP98 (Sus scrofa)
        
        Nuclear Pore Complex (p-2S,3T-NUP98) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        Partially Disassembled NPC [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)

Cellular responses to stimuli (Sus scrofa)

- Cellular responses to stress (Sus scrofa)
  - Cellular response to heat stress (Sus scrofa)
    - Regulation of HSF1-mediated heat shock response (Sus scrofa)
      - NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)

Gene expression (Transcription) (Sus scrofa)

- Gene Silencing by RNA (Sus scrofa)
  - Transcriptional regulation by small RNAs (Sus scrofa)
    - Importin-8 imports AGO2:miRNA into the nucleus (Sus scrofa)
      - Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)

Metabolism of RNA (Sus scrofa)

- Metabolism of non-coding RNA (Sus scrofa)
  - snRNP Assembly (Sus scrofa)
    - snRNP nuclear import and release (Sus scrofa)
      - Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
- Processing of Capped Intron-Containing Pre-mRNA (Sus scrofa)
  - Transport of Mature Transcript to Cytoplasm (Sus scrofa)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Sus scrofa)
      - Transport of the export-competent mRNP complex through the NPC (Sus scrofa)
        
        NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
      - mRNP complex dissociates from cytosolic face of NPC (Sus scrofa)
        
        NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
    - Transport of Mature mRNAs Derived from Intronless Transcripts (Sus scrofa)
      - Transport of Mature mRNA Derived from an Intronless Transcript (Sus scrofa)
        
        Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
      - Transport of the SLBP Dependant Mature mRNA (Sus scrofa)
        
        Docking of Mature Replication Dependent Histone mRNA with the NPC (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
      - Transport of the SLBP independent Mature mRNA (Sus scrofa)
        
        Docking of Mature Histone mRNA complex:TAP at the NPC (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        Release of the SLBP independent Histone mRNA from the NPC (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - SUMOylation (Sus scrofa)
    - SUMO E3 ligases SUMOylate target proteins (Sus scrofa)
      - SUMOylation of DNA damage response and repair proteins (Sus scrofa)
        
        RANBP2 SUMOylates PML with SUMO1 (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        RANBP2 SUMOylates PML with SUMO2 (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        RANBP2 SUMOylates SP100 with SUMO1 (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        RANBP2 SUMOylates SP100 with SUMO2 (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
      - SUMOylation of DNA replication proteins (Sus scrofa)
        
        RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) (Sus scrofa)
        
        RANBP2:RANGAP1-SUMO1:UBE2I:Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
      - SUMOylation of RNA binding proteins (Sus scrofa)
        
        RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
      - SUMOylation of SUMOylation proteins (Sus scrofa)
        
        RANBP2 SUMOylates RANBP2 with SUMO1 (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        RANBP2 SUMOylates RANBP2 with SUMO2 (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
      - SUMOylation of chromatin organization proteins (Sus scrofa)
        
        RANBP2 SUMOylates HDAC4 with SUMO1 (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
        
        RANBP2 SUMOylates HDAC4 with SUMO2,3 (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)
      - SUMOylation of ubiquitinylation proteins (Sus scrofa)
        
        RANBP2 SUMOylates MDM2 with SUMO1 (Sus scrofa)
        
        Nuclear Pore Complex (NPC) [nuclear envelope] (Sus scrofa)
        
        POM121 [nuclear envelope] (Sus scrofa)
        
        Homologues of POM121C [nuclear envelope] (Sus scrofa)
        
        POM121C [nuclear envelope] (Sus scrofa)