Reactome | IL13:p-Y-IL13RA1:p-Y-TYK2 [plasma membrane]

IL13:p-Y-IL13RA1:p-Y-TYK2 [plasma membrane]

Stable Identifier

R-SSC-6786788

Type

Complex

Species

Sus scrofa

Compartment

plasma membrane

Locations in the PathwayBrowser

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Immune System (Sus scrofa)

- Cytokine Signaling in Immune system (Sus scrofa)
  - Signaling by Interleukins (Sus scrofa)
    - Interleukin-4 and Interleukin-13 signaling (Sus scrofa)
      - IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Sus scrofa)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2 [plasma membrane] (Sus scrofa)
      - STAT1,STAT3,STAT6 bind IL13:IL13R type II (Sus scrofa)
        
        IL13-bound tyrosine-phosphorylated IL13 receptor type II with STAT1,STAT3,STAT6 [plasma membrane] (Sus scrofa)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2 [plasma membrane] (Sus scrofa)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2 [plasma membrane] (Sus scrofa)
      - STAT1,STAT3,STAT6 phosphorylation (Sus scrofa)
        
        IL13-bound tyrosine-phosphorylated IL13 receptor type II with STAT1,STAT3,STAT6 [plasma membrane] (Sus scrofa)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2 [plasma membrane] (Sus scrofa)
        
        IL13-bound tyrosine-phosphorylated IL13 receptor type II with phosphorylated STAT1,STAT3,STAT6 [plasma membrane] (Sus scrofa)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2 [plasma membrane] (Sus scrofa)
      - p-Y-STATs dissociate (Sus scrofa)
        
        IL13-bound tyrosine-phosphorylated IL13 receptor type II with phosphorylated STAT1,STAT3,STAT6 [plasma membrane] (Sus scrofa)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2 [plasma membrane] (Sus scrofa)
        
        IL13-bound tyrosine-phosphorylated IL13R type II [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Sus scrofa)
        
        IL13:p-Y-IL13RA1:p-Y-TYK2 [plasma membrane] (Sus scrofa)

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Participates

as a component of

IL13:p-Y-IL13RA1:p-Y-TYK2:p-Y-IL4R:p-Y1007-JAK2 [plasma membrane] (Sus scrofa)

Inferred From

IL13:p-Y-IL13RA1:p-Y-TYK2 [plasma membrane] (Homo sapiens)

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