Reactome | TMED2 [ER to Golgi transport vesicle membrane]

TMED2 [ER to Golgi transport vesicle membrane]

Stable Identifier

R-SSC-5689847

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

ER to Golgi transport vesicle membrane

Synonyms

TMED2, A0A8W4FFC7

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Asparagine N-linked glycosylation (Sus scrofa)
    - Transport to the Golgi and subsequent modification (Sus scrofa)
      - ER to Golgi Anterograde Transport (Sus scrofa)
        
        COPII-mediated vesicle transport (Sus scrofa)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Sus scrofa)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        Nucleotide exchange on RAB1 (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        Vesicle budding (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2 [ER to Golgi transport vesicle membrane] (Sus scrofa)

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - ER to Golgi Anterograde Transport (Sus scrofa)
    - COPII-mediated vesicle transport (Sus scrofa)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Sus scrofa)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2 [ER to Golgi transport vesicle membrane] (Sus scrofa)
      - Nucleotide exchange on RAB1 (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2 [ER to Golgi transport vesicle membrane] (Sus scrofa)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2 [ER to Golgi transport vesicle membrane] (Sus scrofa)
      - Vesicle budding (Sus scrofa)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)
        
        TMED2 [ER to Golgi transport vesicle membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A8W4FFC7

Gene Names

TMED2

Reference Genes

ENSEMBL:ENSSSCG00000009772.4

Other Identifiers

100625917

GO:0001701

GO:0001756

GO:0001843

GO:0001892

GO:0001893

GO:0001947

GO:0005109

GO:0005119

GO:0005783

GO:0005789

GO:0005793

GO:0005794

GO:0006886

GO:0006954

GO:0007029

GO:0007030

GO:0008104

GO:0009306

GO:0010628

GO:0022414

GO:0023052

GO:0032525

GO:0035264

GO:0036211

GO:0036342

GO:0036499

GO:0043226

GO:0043231

GO:0045879

GO:0048598

GO:0048856

GO:0060670

GO:0060716

GO:0060717

GO:0061024

GO:0072595

GO:0072659

GO:0090158

GO:1903077

GO:1903912

GO:1905069

GO:2000638

Ssc.4554.1.S1_at

Participates

as a component of

TMED2:TMED10 tetramer [ER to Golgi transport vesicle membrane] (Sus scrofa)

Other forms of this molecule

TMED2 [transport vesicle]

TMED2 [Golgi membrane]

TMED2 [endoplasmic reticulum membrane]

TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Inferred From

TMED2 [ER to Golgi transport vesicle membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000086598

Ensembl

ENSSSCG00000009772, ENSSSCT00000091916, ENSSSCP00000077573

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