Reactome | TMED10 [endoplasmic reticulum membrane]

TMED10 [endoplasmic reticulum membrane]

Stable Identifier

R-SSC-5689479

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

endoplasmic reticulum membrane

Synonyms

TMED10, A0A286ZV95

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Asparagine N-linked glycosylation (Sus scrofa)
    - Transport to the Golgi and subsequent modification (Sus scrofa)
      - ER to Golgi Anterograde Transport (Sus scrofa)
        
        COPII-mediated vesicle transport (Sus scrofa)
        
        Inner coat assembly and cargo binding (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Loss of SAR1B GTPase (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        SEC31:SEC13 and v-SNARE recruitment (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Vesicle budding (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Cargo concentration in the ER (Sus scrofa)
        
        Inner coat assembly and cargo binding (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer binds GPI anchored proteins (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - ER to Golgi Anterograde Transport (Sus scrofa)
    - COPII-mediated vesicle transport (Sus scrofa)
      - Inner coat assembly and cargo binding (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
      - Loss of SAR1B GTPase (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
      - SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
      - SEC31:SEC13 and v-SNARE recruitment (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
      - Vesicle budding (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
    - Cargo concentration in the ER (Sus scrofa)
      - Inner coat assembly and cargo binding (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
      - TMED2:TMED10 tetramer binds GPI anchored proteins (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Sus scrofa)
    - Golgi-to-ER retrograde transport (Sus scrofa)
      - COPI-dependent Golgi-to-ER retrograde traffic (Sus scrofa)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Sus scrofa)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo:NBAS:RINT1:ZW10:STX18:USE1L:BNIP1 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Golgi-to-ER cargo [endoplasmic reticulum membrane] (Sus scrofa)
        
        SURF4:p24 complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 dimer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)
        
        p24 dimers [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 dimer [endoplasmic reticulum membrane] (Sus scrofa)
        
        TMED10 [endoplasmic reticulum membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A286ZV95

Gene Names

TMED10

Reference Genes

BioGPS Gene:100158015 TMED10

ENSEMBL:ENSSSCG00000035684.3

KEGG:ssc:100158015 TMED10

Monarch:100158015 TMED10

NCBI Gene:100158015 TMED10

UCSC:A0A286ZV95 TMED10

Reference Transcript

RefSeq:XM_001926711.5 TMED10

Other Identifiers

100158015

GO:0005215

GO:0005783

GO:0005789

GO:0005793

GO:0005794

GO:0006886

GO:0006888

GO:0007030

GO:0008320

GO:0016020

GO:0016192

GO:0019905

GO:0030134

GO:0030137

GO:0030667

GO:0031410

GO:0032732

GO:0035964

GO:0042589

GO:0043226

GO:0043231

GO:0045055

GO:0048199

GO:0050714

GO:0055085

GO:0061024

GO:0070765

GO:0071806

GO:0106272

GO:0106273

GO:1902003

Ssc.4120.1.A1_at

Ssc.9761.1.S1_at

Participates

as a component of

Other forms of this molecule

TMED10 [Golgi membrane]

TMED10 [transport vesicle]

TMED10 [endoplasmic reticulum-Golgi intermediate compartment membrane]

TMED10 [ER to Golgi transport vesicle membrane]

Inferred From

TMED10 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

XP_001926746.1

ENSEMBL

ENSSSCP00000035381, ENSSSCT00000046327, ENSSSCG00000035684

VGNC

94054

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