Reactome | XRCC3 [nucleoplasm]

XRCC3 [nucleoplasm]

Stable Identifier

R-SSC-5685303

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

XRCC3, F1S9W9

Locations in the PathwayBrowser

Expand all

DNA Repair (Sus scrofa)

- DNA Double-Strand Break Repair (Sus scrofa)
  - Homology Directed Repair (Sus scrofa)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Sus scrofa)
      - HDR through Homologous Recombination (HRR) (Sus scrofa)
        
        D-loop extension by DNA polymerases (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        Homologous DNA Pairing and Strand Exchange (Sus scrofa)
        
        CX3 complex binds D-loop structures (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        CX3 complex formation (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        Resolution of D-Loop Structures (Sus scrofa)
        
        Resolution of D-loop Structures through Holliday Junction Intermediates (Sus scrofa)
        
        Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Sus scrofa)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        FIGNL1 binds RAD51 (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:FIRRM:FIGNL1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        Ligation of DNA and formation of Holliday structures following repair synthesis (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        MUS81:EME1,EME2 cleaves D-loop (Sus scrofa)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        XRCC3 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1S9W9

Gene Names

XRCC3

Reference Genes

BioGPS Gene:100522195 XRCC3

ENSEMBL:ENSSSCG00000002546.5

Monarch:100522195 XRCC3

NCBI Gene:100522195 XRCC3

UCSC:F1S9W9 XRCC3

Reference Transcript

Other Identifiers

100522195

GO:0000166

GO:0000278

GO:0000400

GO:0000722

GO:0000724

GO:0003677

GO:0003824

GO:0005524

GO:0005634

GO:0005654

GO:0005657

GO:0005694

GO:0005737

GO:0005739

GO:0005829

GO:0006281

GO:0006310

GO:0007010

GO:0007059

GO:0008821

GO:0010824

GO:0016787

GO:0023052

GO:0032200

GO:0033065

GO:0036297

GO:0043226

GO:0045003

GO:0048471

GO:0071140

GO:0090267

GO:0090656

GO:0090737

GO:0140014

GO:0140097

GO:0140299

GO:0140657

GO:0140664

Participates

as an input of

CX3 complex formation (Sus scrofa)

as a component of

CX3 complex [nucleoplasm] (Sus scrofa)

Inferred From

XRCC3 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_013852779.1, XP_013852788.1, XP_013852776.1, XP_013852773.1, XP_013852783.1, XP_013852790.1

ENSEMBL

ENSSSCG00000002546, ENSSSCT00000002829, ENSSSCP00000002757

VGNC

95010

Cite Us!