Reactome | TIMELESS [nucleoplasm]

TIMELESS [nucleoplasm]

Stable Identifier

R-SSC-5684982

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

TIMELESS, F1SLB6

Locations in the PathwayBrowser

Expand all

DNA Repair (Sus scrofa)

- DNA Double-Strand Break Repair (Sus scrofa)
  - Homology Directed Repair (Sus scrofa)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Sus scrofa)
      - Processing of DNA double-strand break ends (Sus scrofa)
        
        Activation of CHEK1 at resected DNA DSBs (Sus scrofa)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Sus scrofa)
        
        TIMELESS:TIPIN [nucleoplasm] (Sus scrofa)
        
        TIMELESS [nucleoplasm] (Sus scrofa)
        
        TIMELESS:TIPIN [nucleoplasm] (Sus scrofa)
        
        TIMELESS [nucleoplasm] (Sus scrofa)
        
        CHEK1 is recruited to resected DNA DSBs (Sus scrofa)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Sus scrofa)
        
        TIMELESS:TIPIN [nucleoplasm] (Sus scrofa)
        
        TIMELESS [nucleoplasm] (Sus scrofa)
        
        TIMELESS:TIPIN [nucleoplasm] (Sus scrofa)
        
        TIMELESS [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SLB6

Gene Names

TIMELESS

Reference Genes

ENSEMBL:ENSSSCG00000000399.5

Other Identifiers

GO:0000076

GO:0000228

GO:0000785

GO:0002009

GO:0003677

GO:0005634

GO:0005654

GO:0005694

GO:0006260

GO:0006281

GO:0006310

GO:0006351

GO:0006355

GO:0006974

GO:0007623

GO:0023052

GO:0030324

GO:0031298

GO:0035861

GO:0042752

GO:0042802

GO:0043111

GO:0043226

GO:0044770

GO:0045892

GO:0048511

GO:0048754

GO:0048856

GO:0072711

GO:0072719

GO:1904976

GO:1905168

GO:2000781

Participates

as a component of

TIMELESS:TIPIN [nucleoplasm] (Sus scrofa)

Inferred From

TIMELESS [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000111602

Ensembl

ENSSSCT00000000431, ENSSSCP00000000425, ENSSSCG00000000399

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