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phospho-MAP3K8 [cytosol]
Stable Identifier
R-SSC-5684259
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
p-S400,T290-MAP3K8, K7GKL4
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-1 family signaling (Sus scrofa)
Interleukin-1 signaling (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
Interleukin-17 signaling (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
Innate Immune System (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
phospho-MAP3K8 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:K7GKL4
Gene Names
MAP3K8
Reference Genes
ENSEMBL:ENSSSCG00000020705.5
Other Identifiers
100622217
GO:0000165
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0004709
GO:0005524
GO:0005829
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0106310
GO:0140096
Ssc.18038.1.A1_at
Participates
as an output of
3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Sus scrofa)
as a component of
NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
p-S927,S932-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] (Sus scrofa)
Other forms of this molecule
phospho-MAP3K8 [cytosol]
MAP3K8 [cytosol]
Inferred From
p-S400,T290-MAP3K8 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 290 (in Homo sapiens)
Coordinate
290
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 400 (in Homo sapiens)
Coordinate
400
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
OpenTargets
ENSG00000107968
Ensembl
ENSSSCG00000020705
,
ENSSSCT00000033089
,
ENSSSCP00000028391
VGNC
98110
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