Reactome | FEN1 [nucleoplasm]

FEN1 [nucleoplasm]

Stable Identifier

R-SSC-54745

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

FEN1, F1RKS3

Locations in the PathwayBrowser

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Cell Cycle (Sus scrofa)

- Cell Cycle, Mitotic (Sus scrofa)
  - S Phase (Sus scrofa)
    - Synthesis of DNA (Sus scrofa)
      - DNA strand elongation (Sus scrofa)
        
        Lagging Strand Synthesis (Sus scrofa)
        
        Processive synthesis on the lagging strand (Sus scrofa)
        
        Removal of the Flap Intermediate (Sus scrofa)
        
        Removal of remaining Flap (Sus scrofa)
        
        FEN1 [nucleoplasm] (Sus scrofa)
- Chromosome Maintenance (Sus scrofa)
  - Telomere Maintenance (Sus scrofa)
    - Extension of Telomeres (Sus scrofa)
      - Telomere C-strand (Lagging Strand) Synthesis (Sus scrofa)
        
        Processive synthesis on the C-strand of the telomere (Sus scrofa)
        
        Removal of the Flap Intermediate from the C-strand (Sus scrofa)
        
        Removal of remaining Flap from the C-strand (Sus scrofa)
        
        FEN1 [nucleoplasm] (Sus scrofa)

DNA Replication (Sus scrofa)

- Synthesis of DNA (Sus scrofa)
  - DNA strand elongation (Sus scrofa)
    - Lagging Strand Synthesis (Sus scrofa)
      - Processive synthesis on the lagging strand (Sus scrofa)
        
        Removal of the Flap Intermediate (Sus scrofa)
        
        Removal of remaining Flap (Sus scrofa)
        
        FEN1 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RKS3

Gene Names

FEN1

Reference Genes

BioGPS Gene:100517749 FEN1

ENSEMBL:ENSSSCG00000063433.1

KEGG:ssc:100517749 FEN1

Monarch:100517749 FEN1

NCBI Gene:100517749 FEN1

UCSC:F1RKS3 FEN1

Reference Transcript

RefSeq:XM_003122627.4 FEN1

Other Identifiers

100517749

GO:0000287

GO:0000781

GO:0003677

GO:0003824

GO:0004518

GO:0004519

GO:0004523

GO:0004527

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0005739

GO:0006260

GO:0006281

GO:0006284

GO:0006974

GO:0008409

GO:0016787

GO:0016788

GO:0017108

GO:0030145

GO:0032991

GO:0043137

GO:0043226

GO:0045876

GO:0046872

GO:0048256

GO:0090304

GO:0140097

GO:0140098

Ssc.21701.1.S1_at

Ssc.21701.2.S1_at

Participates

as an input of

as a component of

as an output of

FEN1 cleaves displaced ssDNA flaps during MMEJ (Sus scrofa)

Inferred From

FEN1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_003122675.1

ENSEMBL

ENSSSCP00000079724, ENSSSCT00000100302, ENSSSCG00000063433

VGNC

88085