Reactome | MBD3 [nucleoplasm]

MBD3 [nucleoplasm]

Stable Identifier

R-SSC-4657010

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

MBD3, F1SDI3

Locations in the PathwayBrowser

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Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase I Transcription (Sus scrofa)
  - RNA Polymerase I Promoter Clearance (Sus scrofa)
    - RNA Polymerase I Transcription Initiation (Sus scrofa)
      - Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Sus scrofa)
        
        TTF-I:Sal Box:CSB:G9a:NuRD [nucleoplasm] (Sus scrofa)
        
        NuRD complex [nucleoplasm] (Sus scrofa)
        
        MBD3 [nucleoplasm] (Sus scrofa)
- RNA Polymerase II Transcription (Sus scrofa)
  - Generic Transcription Pathway (Sus scrofa)
    - Transcriptional Regulation by TP53 (Sus scrofa)
      - Regulation of TP53 Activity (Sus scrofa)
        
        Regulation of TP53 Activity through Acetylation (Sus scrofa)
        
        MTA2-NuRD complex deacetylates TP53 (Sus scrofa)
        
        MTA2-NuRD complex [nucleoplasm] (Sus scrofa)
        
        MBD3 [nucleoplasm] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Intracellular signaling by second messengers (Sus scrofa)
  - PIP3 activates AKT signaling (Sus scrofa)
    - PTEN Regulation (Sus scrofa)
      - Regulation of PTEN gene transcription (Sus scrofa)
        
        SALL4 recruits NuRD to PTEN gene (Sus scrofa)
        
        NuRD complex [nucleoplasm] (Sus scrofa)
        
        MBD3 [nucleoplasm] (Sus scrofa)
        
        SALL4:NuRD:PTEN gene [nucleoplasm] (Sus scrofa)
        
        SALL4:NuRD [nucleoplasm] (Sus scrofa)
        
        NuRD complex [nucleoplasm] (Sus scrofa)
        
        MBD3 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SDI3

Gene Names

MBD3

Reference Genes

ENSEMBL:ENSSSCG00000013435.5

Other Identifiers

100523889

GO:0000122

GO:0000785

GO:0000792

GO:0001701

GO:0003677

GO:0003682

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0006325

GO:0006338

GO:0006346

GO:0006351

GO:0006355

GO:0008327

GO:0009888

GO:0016581

GO:0032991

GO:0043226

GO:0048856

Ssc.23115.1.S1_a_at

Participates

as a component of

Inferred From

MBD3 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000071655

Ensembl

ENSSSCT00000014679, ENSSSCP00000014284, ENSSSCG00000013435

VGNC

90049

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