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phospho-IRF7 [cytosol]
Stable Identifier
R-SSC-450318
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
p-S477,S479-IRF7, A0ZVR0
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Innate Immune System (Sus scrofa)
Cytosolic sensors of pathogen-associated DNA (Sus scrofa)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production (Sus scrofa)
p-IRF7:p-IRF7 translocates to the nucleus (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Sus scrofa)
TRAF3-dependent IRF activation pathway (Sus scrofa)
Dimerization of Phospho IRF3 or phospho IRF7 (Sus scrofa)
IRF3-P:IRF7-P [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
Translocation of phosphorylated IRF3,IRF7 dimers into nucleus (Sus scrofa)
IRF3-P:IRF7-P [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
TRAF6 mediated IRF7 activation (Sus scrofa)
Dimerization of p-IRF7 (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
Translocation of p-IRF7:p-IRF7 to nucleus (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
TICAM1-dependent activation of IRF3/IRF7 (Sus scrofa)
Dimerization of phosphorylated IRF3/IRF7 (Sus scrofa)
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
phosphorylated IRF3 and/or IRF7 dimer [cytosol] (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Sus scrofa)
phosphorylated IRF3 and/or IRF7 dimer [cytosol] (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Sus scrofa)
Dimerization of phosphorylated IRF3/IRF7 (Sus scrofa)
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
phosphorylated IRF3 and/or IRF7 dimer [cytosol] (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Sus scrofa)
phosphorylated IRF3 and/or IRF7 dimer [cytosol] (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Sus scrofa)
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (Sus scrofa)
Dimerization of p-IRF7 (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
Translocation of p-IRF7:p-IRF7 to nucleus (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (Sus scrofa)
Dimerization of p-IRF7 (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
Translocation of p-IRF7:p-IRF7 to nucleus (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
phospho-IRF7 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0ZVR0
Gene Names
IRF7
Reference Genes
BioGPS Gene:100037289 IRF7
ENSEMBL:ENSSSCG00000012853.5
KEGG Gene (Sus scrofa):100037289 IRF7
Monarch:100037289 IRF7
NCBI Gene:100037289 IRF7
Reference Transcript
RefSeq:NM_001097428.1 IRF7
Other Identifiers
100037289
GO:0000785
GO:0000976
GO:0000978
GO:0000981
GO:0000987
GO:0002376
GO:0002753
GO:0002819
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0010468
GO:0016064
GO:0023052
GO:0032481
GO:0032727
GO:0032728
GO:0034124
GO:0034127
GO:0043226
GO:0045893
GO:0045944
GO:0051607
GO:0060337
GO:0060340
GO:0098542
GO:0140110
GO:1990837
Ssc.21162.1.S1_s_at
Ssc.25739.1.S1_at
Participates
as an input of
Dimerization of p-IRF7 (Sus scrofa)
as a member of
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Sus scrofa)
as a component of
IRF3-P:IRF7-P [cytosol] (Sus scrofa)
p-2S-IRF7:p-2S-IRF7 [cytosol] (Sus scrofa)
Other forms of this molecule
phospho-IRF7 [nucleoplasm]
IRF7 [cytosol]
Inferred From
p-S477,S479-IRF7 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 477 (in Homo sapiens)
Coordinate
477
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 479 (in Homo sapiens)
Coordinate
479
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001090897.1
OpenTargets
ENSG00000185507
Ensembl
ENSSSCP00000013664
,
ENSSSCG00000012853
,
ENSSSCT00000014049
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q68871 Q68871
0.508
5
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