Reactome | IL2RA [plasma membrane]

IL2RA [plasma membrane]

Stable Identifier

R-SSC-450046

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

IL2RA, A0A287A7A4

Locations in the PathwayBrowser

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Immune System (Sus scrofa)

- Cytokine Signaling in Immune system (Sus scrofa)
  - Signaling by Interleukins (Sus scrofa)
    - Interleukin-2 family signaling (Sus scrofa)
      - Interleukin receptor SHC signaling (Sus scrofa)
        
        Gab2 binds the p85 subunit of Class 1A PI3 kinases (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Phosphorylated SHC recruits GRB2:SOS1 (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Phosphorylated SHC1 recruits GRB2:GAB2 (Sus scrofa)
        
        Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Phosphorylated SHC1 recruits SHIP (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        SHC1 mediates cytokine-induced phosphorylation of GAB2 (Sus scrofa)
        
        Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        The SHC1:SHIP1 complex is stabilized by GRB2 (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
      - Interleukin-2 signaling (Sus scrofa)
        
        Interleukin-2 receptor alpha binds interleukin-2 (Sus scrofa)
        
        IL2:IL2RA [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta (Sus scrofa)
        
        IL2:IL2RA [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        IL2:IL2RA:IL2RB:JAK1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2RA [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit (Sus scrofa)
        
        IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2:IL2RA:IL2RB:JAK1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2RA [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        IL2:IL2RA:IL2RB:JAK1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2RA [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] (Sus scrofa)
        
        IL2RA:IL2RB:p-JAK1 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Phosphorylated STAT5 is released (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Phosphorylation of IL2RB Y338 enables SHC recruitment (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Recruited STAT5 is phosphorylated (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        SHC1 bound to IL2 receptor is phosphorylated (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        SYK binds IL2RB (Sus scrofa)
        
        IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] (Sus scrofa)
        
        IL2RA:IL2RB:p-JAK1 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] (Sus scrofa)
        
        IL2RA:IL2RB:p-JAK1 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        SYK is a substrate for JAK1 (Sus scrofa)
        
        IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] (Sus scrofa)
        
        IL2RA:IL2RB:p-JAK1 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer:p-JAK1:JAK3:p-SYK [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] (Sus scrofa)
        
        IL2RA:IL2RB:p-JAK1 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Within the IL-2R complex JAK3 phosphorylates JAK1 (Sus scrofa)
        
        IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2:IL2RA:IL2RB:JAK1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2RA [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA:IL2RB:p-JAK1:IL2 [plasma membrane] (Sus scrofa)
        
        IL2RA:IL2RB:p-JAK1 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
    - Interleukin-3, Interleukin-5 and GM-CSF signaling (Sus scrofa)
      - Interleukin receptor SHC signaling (Sus scrofa)
        
        Gab2 binds the p85 subunit of Class 1A PI3 kinases (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Phosphorylated SHC recruits GRB2:SOS1 (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Phosphorylated SHC1 recruits GRB2:GAB2 (Sus scrofa)
        
        Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Phosphorylated SHC1 recruits SHIP (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        SHC1 mediates cytokine-induced phosphorylation of GAB2 (Sus scrofa)
        
        Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        The SHC1:SHIP1 complex is stabilized by GRB2 (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)

Signal Transduction (Sus scrofa)

- MAPK family signaling cascades (Sus scrofa)
  - MAPK1/MAPK3 signaling (Sus scrofa)
    - RAF/MAP kinase cascade (Sus scrofa)
      - RAS GEFs promote RAS nucleotide exchange (Sus scrofa)
        
        RAS GEFs [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Sus scrofa)
        
        IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Sus scrofa)
        
        IL2RA [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287A7A4

Gene Names

IL2RA

Reference Genes

BioGPS Gene:396814 IL2RA

ENSEMBL:ENSSSCG00000022849.4

Monarch:396814 IL2RA

NCBI Gene:396814 IL2RA

UCSC:A0A287A7A4 IL2RA

Reference Transcript

RefSeq:XM_021064060.1 IL2RA

Other Identifiers

396814

GO:0002376

GO:0002664

GO:0002682

GO:0004911

GO:0006954

GO:0006955

GO:0016020

GO:0019976

GO:0038110

Ssc.14476.1.S1_at

Participates

as an input of

Interleukin-2 receptor alpha binds interleukin-2 (Sus scrofa)

as a component of

Inferred From

IL2RA [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_020919719.1

ENSEMBL

ENSSSCG00000022849, ENSSSCP00000039694, ENSSSCT00000037150

VGNC

108275

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