Reactome | IL5 [extracellular region]

IL5 [extracellular region]

Stable Identifier

R-SSC-447159

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

extracellular region

Synonyms

IL5, Q9MYM5

Locations in the PathwayBrowser

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Immune System (Sus scrofa)

- Cytokine Signaling in Immune system (Sus scrofa)
  - Signaling by Interleukins (Sus scrofa)
    - Interleukin-2 family signaling (Sus scrofa)
      - Interleukin receptor SHC signaling (Sus scrofa)
        
        Gab2 binds the p85 subunit of Class 1A PI3 kinases (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Phosphorylated SHC recruits GRB2:SOS1 (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Phosphorylated SHC1 recruits GRB2:GAB2 (Sus scrofa)
        
        Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Phosphorylated SHC1 recruits SHIP (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        SHC1 mediates cytokine-induced phosphorylation of GAB2 (Sus scrofa)
        
        Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        The SHC1:SHIP1 complex is stabilized by GRB2 (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
    - Interleukin-3, Interleukin-5 and GM-CSF signaling (Sus scrofa)
      - 14-3-3 zeta binding allows recruitment of PI3K (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - Activation of STAT5a/b by JAK2 (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc. activated JAK2:STAT5 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - IL3RB is phosphorylated on Ser-585 (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - Interleukin receptor SHC signaling (Sus scrofa)
        
        Gab2 binds the p85 subunit of Class 1A PI3 kinases (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Phosphorylated SHC recruits GRB2:SOS1 (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Phosphorylated SHC1 recruits GRB2:GAB2 (Sus scrofa)
        
        Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Phosphorylated SHC1 recruits SHIP (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        SHC1 mediates cytokine-induced phosphorylation of GAB2 (Sus scrofa)
        
        Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        The SHC1:SHIP1 complex is stabilized by GRB2 (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - Interleukin-5 is a homodimer (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - Interleukin-5 receptor alpha subunit binds Interleukin-5 (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - Interleukin-5:Interleukin-5 receptor alpha binds IL3RB:JAK2 (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - JAK2 is phosphorylated, activated (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - Recruitment of SHC1 is mediated by Y593 of the common beta chain (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - SHP1 and SHP2 bind the common beta chain (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593)-Bc:SHP1, SHP2 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593)-Bc [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - STAT5 is recruited by JAK2 (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc. activated JAK2:STAT5 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, activated JAK2:STAT5 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - The receptor is activated (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        High affinity binding complexes of interleukin receptors using the Common beta chain [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - Tyrosine kinases phosphorylate the receptor (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        Tyrosine kinases that phosphorylate the Common beta chain [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - p-S585-IL3RB binds 14-3-3 proteins (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(S585)-Common beta chain [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(S585)-Common beta chain:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
      - p-STAT5 dissociates from the receptor complex (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2:p-STAT5 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, activated JAK2:p-STAT5 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:Common beta chain:p-JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)

Signal Transduction (Sus scrofa)

- MAPK family signaling cascades (Sus scrofa)
  - MAPK1/MAPK3 signaling (Sus scrofa)
    - RAF/MAP kinase cascade (Sus scrofa)
      - RAS GEFs promote RAS nucleotide exchange (Sus scrofa)
        
        RAS GEFs [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
        
        Interleukin receptor complexes with activated SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Sus scrofa)
        
        High affinity IL-5 receptor complex dimer, inactive JAK2, p(Y593, 628)-Bc [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA:p(Y593, 628)-Bc:JAK2 [plasma membrane] (Sus scrofa)
        
        IL5 homodimer:IL5RA [plasma membrane] (Sus scrofa)
        
        IL5 homodimer [extracellular region] (Sus scrofa)
        
        IL5 [extracellular region] (Sus scrofa)

External Reference Information

External Reference

UniProt:Q9MYM5

Gene Names

IL5

Reference Genes

BioGPS Gene:397409 IL5

ENSEMBL:ENSSSCG00000014278.5 IL5

ENSEMBL:ENSSSCG00005044326.1 IL5

ENSEMBL:ENSSSCG00015037111.1 IL5

ENSEMBL:ENSSSCG00025062360.1 IL5

ENSEMBL:ENSSSCG00030057738.1 IL5

ENSEMBL:ENSSSCG00035033625.1 IL5

ENSEMBL:ENSSSCG00040029041.1 IL5

ENSEMBL:ENSSSCG00045013941.1 IL5

ENSEMBL:ENSSSCG00055003507.1 IL5

ENSEMBL:ENSSSCG00060053373.1

ENSEMBL:ENSSSCG00065016812.1 IL5

ENSEMBL:ENSSSCG00070019980.1 IL5

KEGG Gene (Sus scrofa):397409 IL5

Monarch:397409 IL5

NCBI Gene:397409 IL5

Reference Transcript

RefSeq:NM_214205.1 IL5

Other Identifiers

397409

GO:0002376

GO:0002639

GO:0005125

GO:0005137

GO:0005576

GO:0005615

GO:0006351

GO:0006355

GO:0006955

GO:0008083

GO:0023052

GO:0036211

GO:0038043

GO:0045893

GO:0048018

GO:0050731

GO:0065003

GO:0071803

GO:0098772

Ssc.528.1.S1_at

Participates

as an input of

Interleukin-5 is a homodimer (Sus scrofa)

as a component of

IL5 homodimer [extracellular region] (Sus scrofa)

Inferred From

IL5 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_999370.1

OpenTargets

ENSG00000113525

Ensembl

ENSSSCG00000014278, ENSSSCT00000015601, ENSSSCP00000015189

VGNC

99765

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