Reactome | INSL3 [extracellular region]

INSL3 [extracellular region]

Stable Identifier

R-SSC-444906

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

extracellular region

Synonyms

INSL3(21-55), P51461

Locations in the PathwayBrowser

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Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (s) signalling events (Sus scrofa)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Sus scrofa)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Sus scrofa)
        
        RXFP2:RXFP2 ligands [plasma membrane] (Sus scrofa)
        
        RXFP2 ligands [extracellular region] (Sus scrofa)
        
        Insulin-like peptide 3 [extracellular region] (Sus scrofa)
        
        INSL3 [extracellular region] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Sus scrofa)
        
        RXFP2:RXFP2 ligands [plasma membrane] (Sus scrofa)
        
        RXFP2 ligands [extracellular region] (Sus scrofa)
        
        Insulin-like peptide 3 [extracellular region] (Sus scrofa)
        
        INSL3 [extracellular region] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        Relaxin receptors (Sus scrofa)
        
        Relaxin receptor 2 binds relaxin 2 and INSL3 (Sus scrofa)
        
        RXFP2 ligands [extracellular region] (Sus scrofa)
        
        Insulin-like peptide 3 [extracellular region] (Sus scrofa)
        
        INSL3 [extracellular region] (Sus scrofa)
        
        RXFP2:RXFP2 ligands [plasma membrane] (Sus scrofa)
        
        RXFP2 ligands [extracellular region] (Sus scrofa)
        
        Insulin-like peptide 3 [extracellular region] (Sus scrofa)
        
        INSL3 [extracellular region] (Sus scrofa)

External Reference Information

External Reference

UniProt:P51461

Gene Names

INSL3

Reference Genes

BioGPS Gene:397024 INSL3

ENSEMBL:ENSSSCG00000013887.5 INSL3

ENSEMBL:ENSSSCG00015080416.1 INSL3

ENSEMBL:ENSSSCG00025046452.1

ENSEMBL:ENSSSCG00030055891.1 INSL3

ENSEMBL:ENSSSCG00035020931.1 INSL3

ENSEMBL:ENSSSCG00040048743.1 INSL3

ENSEMBL:ENSSSCG00045022115.1 INSL3

ENSEMBL:ENSSSCG00050071610.1 INSL3

ENSEMBL:ENSSSCG00055026398.1 INSL3

ENSEMBL:ENSSSCG00060027239.1 INSL3

ENSEMBL:ENSSSCG00065007868.1 INSL3

ENSEMBL:ENSSSCG00070015894.1 INSL3

KEGG Gene (Sus scrofa):397024 INSL3

Monarch:397024 INSL3

NCBI Gene:397024 INSL3

Reference Transcript

RefSeq:NM_213970.1 INSL3

Other Identifiers

397024

GO:0002020

GO:0005179

GO:0005576

GO:0010634

GO:0042060

GO:0048018

GO:0048870

GO:0090303

GO:0098772

Ssc.11990.1.S1_at

Participates

as a component of

Insulin-like peptide 3 [extracellular region] (Sus scrofa)

Other forms of this molecule

INSL3 [extracellular region]

Inferred From

INSL3(21-55) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_999135.1

OpenTargets

ENSG00000248099

Ensembl

ENSSSCG00000013887, ENSSSCT00000015173, ENSSSCP00000014767

VGNC

107147

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