Reactome | S1PR2 [plasma membrane]

S1PR2 [plasma membrane]

Stable Identifier

R-SSC-419419

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

S1PR2, F1S3I6

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (i) signalling events (Sus scrofa)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        S1PR2-5:S1P [plasma membrane] (Sus scrofa)
        
        S1PR2-5 [plasma membrane] (Sus scrofa)
        
        S1PR2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        S1PR2-5:S1P [plasma membrane] (Sus scrofa)
        
        S1PR2-5 [plasma membrane] (Sus scrofa)
        
        S1PR2 [plasma membrane] (Sus scrofa)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        S1PR2-5:S1P [plasma membrane] (Sus scrofa)
        
        S1PR2-5 [plasma membrane] (Sus scrofa)
        
        S1PR2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        S1PR2-5:S1P [plasma membrane] (Sus scrofa)
        
        S1PR2-5 [plasma membrane] (Sus scrofa)
        
        S1PR2 [plasma membrane] (Sus scrofa)
      - The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        S1PR2-5:S1P [plasma membrane] (Sus scrofa)
        
        S1PR2-5 [plasma membrane] (Sus scrofa)
        
        S1PR2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        S1PR2-5:S1P [plasma membrane] (Sus scrofa)
        
        S1PR2-5 [plasma membrane] (Sus scrofa)
        
        S1PR2 [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Lysosphingolipid and LPA receptors (Sus scrofa)
        
        S1PR2-5 bind S1P (Sus scrofa)
        
        S1PR2-5 [plasma membrane] (Sus scrofa)
        
        S1PR2 [plasma membrane] (Sus scrofa)
        
        S1PR2-5:S1P [plasma membrane] (Sus scrofa)
        
        S1PR2-5 [plasma membrane] (Sus scrofa)
        
        S1PR2 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1S3I6

Gene Names

S1PR2

Reference Genes

BioGPS Gene:100511551 S1PR2

ENSEMBL:ENSSSCG00000013658.5

ENSEMBL:ENSSSCG00005031515.1 S1PR2

KEGG Gene (Sus scrofa):100511551 S1PR2

Monarch:100511551 S1PR2

NCBI Gene:100511551 S1PR2

Reference Transcript

RefSeq:NM_001243854.1 S1PR2

Other Identifiers

100511551

GO:0001664

GO:0003376

GO:0004930

GO:0005178

GO:0005737

GO:0005886

GO:0007010

GO:0007186

GO:0007189

GO:0008528

GO:0010800

GO:0016020

GO:0019222

GO:0023052

GO:0030036

GO:0030154

GO:0036211

GO:0038036

GO:0046847

GO:0048856

GO:0050877

GO:0060079

GO:0060089

GO:0090394

GO:0098794

GO:1903142

Ssc.5467.1.A1_at

Ssc.5467.2.S1_at

Participates

as a member of

S1PR2-5 [plasma membrane] (Sus scrofa)

Inferred From

S1PR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001230783.1

OpenTargets

ENSG00000267534

Ensembl

ENSSSCP00000072860, ENSSSCT00000014922, ENSSSCT00000066775, ENSSSCT00000069735, ENSSSCP00000014521, ENSSSCP00000068844, ENSSSCG00000013658

VGNC

92552