Reactome | ADORA2B [plasma membrane]

ADORA2B [plasma membrane]

Stable Identifier

R-SSC-418898

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

ADORA2B, A0A287A5E9

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (s) signalling events (Sus scrofa)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Sus scrofa)
        
        ADORA2B:Ade-Rib [plasma membrane] (Sus scrofa)
        
        ADORA2B [plasma membrane] (Sus scrofa)
        
        Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Sus scrofa)
        
        ADORA2B:Ade-Rib [plasma membrane] (Sus scrofa)
        
        ADORA2B [plasma membrane] (Sus scrofa)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Sus scrofa)
        
        ADORA2A,B:Ade-Rib [plasma membrane] (Sus scrofa)
        
        ADORA2A,B [plasma membrane] (Sus scrofa)
        
        ADORA2B [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Sus scrofa)
        
        ADORA2A,B:Ade-Rib [plasma membrane] (Sus scrofa)
        
        ADORA2A,B [plasma membrane] (Sus scrofa)
        
        ADORA2B [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Nucleotide-like (purinergic) receptors (Sus scrofa)
        
        Adenosine P1 receptors (Sus scrofa)
        
        ADORA2A,B bind Ade-Rib (Sus scrofa)
        
        ADORA2A,B [plasma membrane] (Sus scrofa)
        
        ADORA2B [plasma membrane] (Sus scrofa)
        
        ADORA2A,B:Ade-Rib [plasma membrane] (Sus scrofa)
        
        ADORA2A,B [plasma membrane] (Sus scrofa)
        
        ADORA2B [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287A5E9

Gene Names

ADORA2B

Reference Genes

ENSEMBL:ENSSSCG00000035051.3

Reference Transcript

RefSeq:XM_005658145.2 ADORA2B

Other Identifiers

606745

GO:0001609

GO:0001973

GO:0002376

GO:0002882

GO:0003012

GO:0003013

GO:0004930

GO:0005886

GO:0006954

GO:0007165

GO:0007186

GO:0007189

GO:0010575

GO:0010753

GO:0016020

GO:0016192

GO:0019934

GO:0023052

GO:0031668

GO:0032722

GO:0032755

GO:0043303

GO:0043306

GO:0045202

GO:0050896

GO:0060087

GO:0060089

GO:0098685

GO:0098793

GO:0098978

GO:0099171

GO:0110165

Participates

as a component of

ADORA2B:Ade-Rib [plasma membrane] (Sus scrofa)

as a member of

ADORA2A,B [plasma membrane] (Sus scrofa)

Inferred From

ADORA2B [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_005658202.2

OpenTargets

ENSG00000170425

Ensembl

ENSSSCP00000039169, ENSSSCT00000040616, ENSSSCG00000035051

VGNC

85149