Reactome | phospho-EFNB3 [plasma membrane]

phospho-EFNB3 [plasma membrane]

Stable Identifier

R-SSC-3928388

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

p-Y318,Y323,Y337-EFNB3, B0LDT4

Locations in the PathwayBrowser

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Developmental Biology (Sus scrofa)

- Nervous system development (Sus scrofa)
  - Axon guidance (Sus scrofa)
    - EPH-Ephrin signaling (Sus scrofa)
      - Ephrin signaling (Sus scrofa)
        
        EFNB:GRB4 binds GIT1 (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)
        
        GIT1 binds bPIX (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)
        
        PAK binds RAC and bPIX (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)
        
        PAKs autophosphorylate (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)
        
        PAKs phosphorylate MLC (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)
        
        bPIX exchanges GTP for GDP on RAC, activating it (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)
        
        p-EFNB binds GRB4 (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Sus scrofa)
        
        EPHBs:p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        p-3Y-EFNBs [plasma membrane] (Sus scrofa)
        
        phospho-EFNB3 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:B0LDT4

Gene Names

EFNB3

Reference Genes

BioGPS Gene:100135672 EFNB3

ENSEMBL:ENSSSCG00000017948.5

KEGG Gene (Sus scrofa):100135672 EFNB3

Monarch:100135672 EFNB3

NCBI Gene:100135672 EFNB3

Reference Transcript

RefSeq:NM_001114285.1 EFNB3

Other Identifiers

100135672

GO:0002376

GO:0005886

GO:0007155

GO:0007411

GO:0007628

GO:0016020

GO:0016198

GO:0023052

GO:0030154

GO:0031295

GO:0042734

GO:0046875

GO:0048013

GO:0048856

GO:0050771

GO:0098686

GO:0098978

GO:0099557

Ssc.27504.1.S1_at

Participates

as a member of

p-3Y-EFNBs [plasma membrane] (Sus scrofa)

Other forms of this molecule

EFNB3 [plasma membrane]

Inferred From

p-Y318,Y323,Y337-EFNB3 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 318 (in Homo sapiens)

Coordinate

318

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 323 (in Homo sapiens)

Coordinate

323

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 337 (in Homo sapiens)

Coordinate

337

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_001107757.1

OpenTargets

ENSG00000108947

Ensembl

ENSSSCP00000019014, ENSSSCG00000017948, ENSSSCT00000019532

VGNC

87578

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