Reactome | HTR2B [plasma membrane]

HTR2B [plasma membrane]

Stable Identifier

R-SSC-390967

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

HTR2B, F1SMV8

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (q) signalling events (Sus scrofa)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        HTR2A-C:5HT [plasma membrane] (Sus scrofa)
        
        HTR2A-C [plasma membrane] (Sus scrofa)
        
        HTR2B [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        HTR2A-C:5HT [plasma membrane] (Sus scrofa)
        
        HTR2A-C [plasma membrane] (Sus scrofa)
        
        HTR2B [plasma membrane] (Sus scrofa)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        HTR2A-C:5HT [plasma membrane] (Sus scrofa)
        
        HTR2A-C [plasma membrane] (Sus scrofa)
        
        HTR2B [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        HTR2A-C:5HT [plasma membrane] (Sus scrofa)
        
        HTR2A-C [plasma membrane] (Sus scrofa)
        
        HTR2B [plasma membrane] (Sus scrofa)
      - The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
        
        GPCRs that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        HTR2A-C [plasma membrane] (Sus scrofa)
        
        HTR2B [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        HTR2A-C:5HT [plasma membrane] (Sus scrofa)
        
        HTR2A-C [plasma membrane] (Sus scrofa)
        
        HTR2B [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Amine ligand-binding receptors (Sus scrofa)
        
        Serotonin receptors (Sus scrofa)
        
        5-HT2 receptor can bind serotonin (Sus scrofa)
        
        HTR2A-C [plasma membrane] (Sus scrofa)
        
        HTR2B [plasma membrane] (Sus scrofa)
        
        HTR2A-C:5HT [plasma membrane] (Sus scrofa)
        
        HTR2A-C [plasma membrane] (Sus scrofa)
        
        HTR2B [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SMV8

Gene Names

HTR2B

Reference Genes

BioGPS Gene:396837 HTR2B

ENSEMBL:ENSSSCG00000016273.5

ENSEMBL:ENSSSCG00005039968.1 HTR2B

KEGG Gene (Sus scrofa):396837 HTR2B

Monarch:396837 HTR2B

NCBI Gene:396837 HTR2B

Reference Transcript

Other Identifiers

396837

GO:0001587

GO:0001755

GO:0001819

GO:0001938

GO:0001965

GO:0002031

GO:0003007

GO:0003012

GO:0003013

GO:0003300

GO:0004930

GO:0004993

GO:0005096

GO:0005634

GO:0005654

GO:0005737

GO:0005886

GO:0006629

GO:0006874

GO:0006939

GO:0007165

GO:0007186

GO:0007187

GO:0007200

GO:0007205

GO:0007208

GO:0007268

GO:0007507

GO:0007610

GO:0008284

GO:0009410

GO:0010513

GO:0012501

GO:0014033

GO:0014827

GO:0016020

GO:0016192

GO:0016310

GO:0019722

GO:0019934

GO:0023052

GO:0030154

GO:0030425

GO:0030594

GO:0042310

GO:0043066

GO:0043123

GO:0043226

GO:0043491

GO:0045202

GO:0048598

GO:0048856

GO:0048870

GO:0050795

GO:0051209

GO:0051378

GO:0051781

GO:0055065

GO:0055085

GO:0060089

GO:0070371

GO:0070374

GO:0070528

GO:0071502

GO:0098664

GO:0098666

GO:0098772

Ssc.16145.1.S1_at

Participates

as a member of

HTR2A-C [plasma membrane] (Sus scrofa)

Inferred From

HTR2B [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_013840016.1, NP_001157491.1, XP_005672326.1

OpenTargets

ENSG00000135914

Ensembl

ENSSSCT00000017721, ENSSSCG00000016273, ENSSSCP00000017240

VGNC

96365