Reactome | TPM2 [cytosol]

TPM2 [cytosol]

Stable Identifier

R-SSC-390552

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

TPM2, A0A287AN33

Locations in the PathwayBrowser

Expand all

Muscle contraction (Sus scrofa)

- Smooth Muscle Contraction (Sus scrofa)
  - ATP Hydrolysis By Myosin (Sus scrofa)
    - ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
      - Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
    - ATP:Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
      - Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
  - Calcium Binds Caldesmon (Sus scrofa)
    - Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
      - Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
    - Inactive Myosin Actin Contractile Complex [plasma membrane] (Sus scrofa)
      - Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
  - Myosin Binds ATP (Sus scrofa)
    - ATP:Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
      - Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
    - p-S CALD1-Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
      - Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
  - Release Of ADP From Myosin (Sus scrofa)
    - ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
      - Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
    - Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
      - Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
- Striated Muscle Contraction (Sus scrofa)
  - ATP Hydrolysis By Myosin (Sus scrofa)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
  - Calcium Binds Troponin-C (Sus scrofa)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
    - Inactive Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament [cytosol] (Sus scrofa)
        
        Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
  - Myosin Binds ATP (Sus scrofa)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
  - Release Of ADP From Myosin (Sus scrofa)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Sus scrofa)
        
        Tropomyosin [cytosol] (Sus scrofa)
        
        TPM2 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287AN33

Gene Names

TPM2

Reference Genes

ENSEMBL:ENSSSCG00000005316.5

Other Identifiers

396693

GO:0003779

GO:0005856

GO:0008092

GO:0043226

Ssc.20571.2.S1_a_at

Ssc.20571.2.S1_at

Participates

as a member of

Tropomyosin [cytosol] (Sus scrofa)

Inferred From

TPM2 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000198467

Ensembl

ENSSSCT00000053274, ENSSSCP00000045307, ENSSSCG00000005316

VGNC

94338