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CDC42:GTP, RAC1:GTP [plasma membrane]
Stable Identifier
R-SSC-389778
Type
Set [DefinedSet]
Species
Sus scrofa
Compartment
plasma membrane
Synonyms
Active RAC1/CDC42
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Costimulation by the CD28 family (Sus scrofa)
CD28 co-stimulation (Sus scrofa)
CD28 dependent Vav1 pathway (Sus scrofa)
Activation of PAKs by RAC1 and CDC42 (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
Innate Immune System (Sus scrofa)
Fcgamma receptor (FCGR) dependent phagocytosis (Sus scrofa)
Regulation of actin dynamics for phagocytic cup formation (Sus scrofa)
Autophosphorylation of PAK1 (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1 and CDC42 activate PAK1 (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
Signal Transduction (Sus scrofa)
MAPK family signaling cascades (Sus scrofa)
MAPK6/MAPK4 signaling (Sus scrofa)
Activation of PAKs by RAC1 and CDC42 (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
Autophosphorylation of PAK1,2,3 (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Sus scrofa)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase Effectors (Sus scrofa)
RHO GTPases activate IQGAPs (Sus scrofa)
GTP-bound RAC1 and CDC42 bind IQGAPs (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Sus scrofa)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
IQGAP1 binds CLIP1 and microtubules (Sus scrofa)
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Sus scrofa)
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
IQGAPs bind CALM1 (Sus scrofa)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Sus scrofa)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
IQGAPs bind F-actin, which is inhibited by calmodulin (Sus scrofa)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Sus scrofa)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Sus scrofa)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RHO GTPases activate PAKs (Sus scrofa)
Autophosphorylation of PAK1,2,3 (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Sus scrofa)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1 and CDC42 activate PAK1 (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
RAC1 and CDC42 activate PAK2 (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Sus scrofa)
CDC42:GTP, RAC1:GTP [plasma membrane] (Sus scrofa)
Participants
members
CDC42:GTP [plasma membrane] (Sus scrofa)
RAC1:GTP [plasma membrane] (Sus scrofa)
Participant Of
hasComponent
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane]
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane]
RAC1,CDC42:GTP:IQGAP1 [plasma membrane]
RAC1,CDC42:GTP:IQGAPs [plasma membrane]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane]
input
Activation of PAKs by RAC1 and CDC42
GTP-bound RAC1 and CDC42 bind IQGAPs
RAC1 and CDC42 activate PAK1
RAC1 and CDC42 activate PAK2
output
Autophosphorylation of PAK1
Autophosphorylation of PAK1,2,3
Inferred From
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
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