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MAP3K8 [cytosol]
Stable Identifier
R-SSC-389388
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
MAP3K8, K7GKL4
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Costimulation by the CD28 family (Sus scrofa)
CD28 co-stimulation (Sus scrofa)
CD28 dependent PI3K/Akt signaling (Sus scrofa)
p-S400-Cot phosphorylates NIK (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-1 family signaling (Sus scrofa)
Interleukin-1 signaling (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
Interleukin-17 signaling (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
Innate Immune System (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
MAP kinase activation (Sus scrofa)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
MAP3K8 is phosphorylated (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
MAP3K8 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:K7GKL4
Gene Names
MAP3K8
Reference Genes
ENSEMBL:ENSSSCG00000020705.5
Other Identifiers
100622217
GO:0000165
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0004709
GO:0005524
GO:0005829
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0106310
GO:0140096
Ssc.18038.1.A1_at
Participates
as a component of
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Sus scrofa)
NFKB1:MAP3K8:TNIP2 [cytosol] (Sus scrofa)
as an input of
NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Sus scrofa)
Other forms of this molecule
phospho-MAP3K8 [cytosol]
phospho-MAP3K8 [cytosol]
Inferred From
MAP3K8 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000107968
Ensembl
ENSSSCG00000020705
,
ENSSSCT00000033089
,
ENSSSCP00000028391
VGNC
98110
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