Reactome | MC2R [plasma membrane]

MC2R [plasma membrane]

Stable Identifier

R-SSC-388600

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

MC2R, Q8HYN8

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (s) signalling events (Sus scrofa)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Sus scrofa)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Sus scrofa)
        
        POMC(138-176):MC2R [plasma membrane] (Sus scrofa)
        
        MC2R [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Sus scrofa)
        
        POMC(138-176):MC2R [plasma membrane] (Sus scrofa)
        
        MC2R [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        POMC(138-176) binds MC2R (Sus scrofa)
        
        MC2R [plasma membrane] (Sus scrofa)
        
        POMC(138-176):MC2R [plasma membrane] (Sus scrofa)
        
        MC2R [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:Q8HYN8

Gene Names

MC2R

Reference Genes

BioGPS Gene:100739231 MC2R

ENSEMBL:ENSSSCG00000039227.3

ENSEMBL:ENSSSCG00005002526.1 MC2R

ENSEMBL:ENSSSCG00045030454.1 MC2R

ENSEMBL:ENSSSCG00070026700.1 MC2R

KEGG Gene (Sus scrofa):100739231 MC2R

Monarch:100739231 MC2R

NCBI Gene:100739231 MC2R

Reference Transcript

Other Identifiers

100739231

GO:0007189

GO:0023052

Ssc.16127.1.S1_at

Participates

as an input of

POMC(138-176) binds MC2R (Sus scrofa)

as a component of

POMC(138-176):MC2R [plasma membrane] (Sus scrofa)

Inferred From

MC2R [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_003482080.1, XP_013854659.1

OpenTargets

ENSG00000185231

Ensembl

ENSSSCG00000039227, ENSSSCT00000045304, ENSSSCP00000074587

VGNC

99701

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