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mTORC1 [cytosol]
Stable Identifier
R-SSC-377400
Type
Complex
Species
Sus scrofa
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Autophagy (Sus scrofa)
Macroautophagy (Sus scrofa)
Active MTORC1 binds the ULK1 complex (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
Active MTORC1 phosphorylates ULK1 (Sus scrofa)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
Rheb in the MTORC1 complex hydrolyses GTP (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Sus scrofa)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to starvation (Sus scrofa)
Amino acids regulate mTORC1 (Sus scrofa)
RRAGA,B hydrolyzes GTP (Sus scrofa)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Sus scrofa)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1 binds RHEB:GTP (Sus scrofa)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Sus scrofa)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
TP53 Regulates Metabolic Genes (Sus scrofa)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
PIP3 activates AKT signaling (Sus scrofa)
PTEN Regulation (Sus scrofa)
Regulation of PTEN gene transcription (Sus scrofa)
MAF1 translocates to the nucleus (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1 phosphorylates MAF1 (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
MTOR signalling (Sus scrofa)
AKT1S1 (PRAS40) binds mTORC1 (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
Energy dependent regulation of mTOR by LKB1-AMPK (Sus scrofa)
AMPK phosphorylates Raptor in the mTORC1 complex (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
Formation of active mTORC1 complex (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Sus scrofa)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Sus scrofa)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1 phosphorylates AKT1S1 (Sus scrofa)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Sus scrofa)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Sus scrofa)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1-mediated signalling (Sus scrofa)
Phosphorylation of 4E-BP1 by activated mTORC1 (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Sus scrofa)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Sus scrofa)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Sus scrofa)
Active mTORC1 complex [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
mTORC1 [cytosol] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
MLST8 [cytosol]
(Sus scrofa)
MTOR [cytosol]
(Sus scrofa)
RPTOR [cytosol]
(Sus scrofa)
Participates
as an input of
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Sus scrofa)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Sus scrofa)
as a component of
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Sus scrofa)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Sus scrofa)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Sus scrofa)
Inferred From
mTORC1 [cytosol]
(Homo sapiens)
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