Reactome | NPB [extracellular region]

NPB [extracellular region]

Stable Identifier

R-SSC-374794

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

extracellular region

Synonyms

NPB(25-48), A0A287BN94

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (i) signalling events (Sus scrofa)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W [extracellular region] (Sus scrofa)
        
        NPB [extracellular region] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W [extracellular region] (Sus scrofa)
        
        NPB [extracellular region] (Sus scrofa)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W [extracellular region] (Sus scrofa)
        
        NPB [extracellular region] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W [extracellular region] (Sus scrofa)
        
        NPB [extracellular region] (Sus scrofa)
      - The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W [extracellular region] (Sus scrofa)
        
        NPB [extracellular region] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W [extracellular region] (Sus scrofa)
        
        NPB [extracellular region] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        GPCR neuropeptide receptor binds neuropeptides B and W (Sus scrofa)
        
        Neuropeptides B/W [extracellular region] (Sus scrofa)
        
        NPB [extracellular region] (Sus scrofa)
        
        Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] (Sus scrofa)
        
        Neuropeptides B/W [extracellular region] (Sus scrofa)
        
        NPB [extracellular region] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287BN94

Gene Names

NPB

Reference Genes

ENSEMBL:ENSSSCG00000035837.3

Other Identifiers

110255934

GO:0001664

GO:0005576

GO:0007186

GO:0007631

GO:0023052

Participates

as a member of

Neuropeptides B/W [extracellular region] (Sus scrofa)

Other forms of this molecule

NPB [extracellular region]

Inferred From

NPB(25-48) [extracellular region] (Homo sapiens)

Cross References

OpenTargets

ENSG00000183979

Ensembl

ENSSSCG00000035837, ENSSSCP00000057632, ENSSSCT00000045778

VGNC

90841